Clone:
REA884
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
FC
Alternative names:
TCR Vbeta6, TCR Vb6

Specifications for TCR Vβ6 Antibody, anti-mouse, REAfinity™

Overview

Clone REA884 recognizes the mouse V beta 6 T cell receptor (TCR Vβ6). The T cell receptor is responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules and plays an important role in T cell mediated immune responses. It is a disulfide-linked membrane-anchored heterodimeric glycoprotein normally consisting of the highly variable α and β chains expressed as part of a complex with the invariant CD3 chain molecules. The α and β TCR chains are composed of constant and variable regions, each encoded by distinct gene segments. REA884 recognizes TCR Vβ6 on mouse strains with the a (e.g., C57BR and SJL) and b haplotypes (e.g., BALB/c, C3H, and DBA/1).
Additional information: Clone REA884 displays negligible binding to Fc receptors.

Alternative names

TCR Vbeta6, TCR Vb6

Detailed product information

Technical specifications

CloneREA884
Clonalitymonoclonal
Isotyperecombinant human IgG1
Isotype controlREA Control Antibody, human IgG1
Hostcell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Speciesmouse
AntigenTCR Vβ6
Alternative names of antigenTCR Vbeta6, TCR Vb6
Distribution of antigenT cells
Entrez Gene ID100124662
RRIDAB_2726732, AB_2726647, AB_2726733, AB_2726648, AB_2726734, AB_2726649, AB_2726735

References for TCR Vβ6 Antibody, anti-mouse, REAfinity™

Publications

  1. Anderson, G. D. et al. (1989)
    MHC class II A alpha and E alpha molecules determine the clonal deletion of V beta 6
    +
    T cells. Studies with recombinant and transgenic mice.
    J. Immunol. 143(11): 3757-3761
  2. Rudy, C. K. et al. (1992) Mls-1-like superantigen in the MA/MyJ mouse is encoded by a new mammary tumor provirus that is distinct from Mtv-7. J. Exp. Med. 175(6): 1613-1621

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