Clone:
REA1062
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
FC, MC
Alternative names:
TCR Vb5.1, TCR Vbeta5.1, V beta 5.1

Specifications for TCR Vβ5.1 Antibody, anti-human, REAfinity™

Overview

Clone REA1062 recognizes the human variable beta 5.1 subunit of the α/β T cell receptor (TCR Vβ5.1), a member of the Ig superfamily. The TCR is a heterodimeric glycoprotein associated with the CD3 antigen. The α and β TCR chains are composed of constant and variable regions, each encoded by distinct gene segments. TCR Vβ5.1 is a variant of the TCR β chain. α/β T cells express a diverse α/β TCR repertoire that specifically co-recognizes self or foreign antigen bound to antigen-presenting molecules, which thereby leads to T cell–mediated immunity. REA1062 does not recognize Vβ5.2 or Vβ5.3.
Additional information: Clone REA1062 displays negligible binding to Fc receptors.

Alternative names

TCR Vb5.1, TCR Vbeta5.1, V beta 5.1

Detailed product information

Technical specifications

CloneREA1062
Clonalitymonoclonal
Isotyperecombinant human IgG1
Isotype controlREA Control Antibody (S), human IgG1
Hostcell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Specieshuman
AntigenTCR Vβ5.1
Alternative names of antigenTCR Vb5.1, TCR Vbeta5.1, V beta 5.1
Molecular mass of antigen [kDa]10
Distribution of antigenT cells, pan T cells
Entrez Gene ID28614
RRIDAB_2733691, AB_2733898, AB_2733899, AB_2733454, AB_2733455, AB_2733015, AB_2733016, AB_2733281, AB_2733282, AB_2733568, AB_2733569, AB_2733690

References for TCR Vβ5.1 Antibody, anti-human, REAfinity™

Publications

  1. Concannon, P. et al. (1986) Diversity and structure of human T-cell receptor beta-chain variable region genes. Proc. Natl. Acad. Sci. U.S.A. 83(17): 6598-6602
  2. Wei, S. et al. (1994) The extent of the human germline T-cell receptor V beta gene segment repertoire. Immunogenetics 40(1): 27-36

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