Clone:
8e11
Type of antibody:
Primary antibodies
Isotype:
mouse IgG1κ
Applications:
FC

Specifications for SSEA-5 Antibody, anti-human

Overview

Clone 8e11 recognizes the human stage-specific embryonic antigen-5 (SSEA-5) antigen, an oligosaccharide that contains the motif Fucα1-2Galβ1-3GlcNAcβ, also known as the H type-1 (H-1) antigen. SSEA-5 is highly and specifically expressed on undifferentiated embryonic stem cells and pluripotent stem cells. It is also expressed on the surface of cells in the inner cell mass of the human blastocyst during embryogenesis and expression is rapidly down-regulated upon cellular differentiation.

Detailed product information

Technical specifications

Clone8e11
Clonalitymonoclonal
Isotypemouse IgG1κ
Isotype controlIsotype Control Antibody, mouse IgG1
Hostmouse
Type of antibodyPrimary antibodies
Specieshuman
AntigenSSEA-5
Distribution of antigenstem cells, ES and iPS cells
RRIDAB_2857583, AB_2857580, AB_2653531, AB_2653532, AB_2653537, AB_2653538, AB_2653539, AB_2653540, AB_2653541, AB_2653542, AB_2653543, AB_2653544, AB_2653545, AB_2653546, AB_2653547

Resources for SSEA-5 Antibody, anti-human

References for SSEA-5 Antibody, anti-human

Publications

  1. Itskovitz-Eldor, J. (2011) A panel of glycan cell surface markers define pluripotency state and promote safer cell-based therapies. Cell Stem Cell 9(4): 291-292
  2. Tang, C. et al. (2011) An antibody against SSEA-5 glycan on human pluripotent stem cells enables removal of teratoma-forming cells. Nat. Biotechnol. 29(9): 829-834

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