Clone:
REA908
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
MICS, IF, IHC
Alternative names:
CKAP4, Plasma Cell, Climp-63

Specifications for Plasma Cell Antibody, anti-human, REAfinity™

Overview

Clone REA908 recognizes the human p63 protein, an intracellular type II transmembrane protein located in the reticular subdomain of the rough endoplasmic reticulum (ER). p63 is mainly found in normal and neoplastic plasma cells, but also in melanocytic cells, melanoma cells, epithelial cells, and osteoblasts from bone marrow and is able to differentiate lymphoplasmacytoid lymphoma from lymphocytic and follicular lymphoma. Is is suggested, that p63 is involved in protein processing or secretion. It binds microtubules in vivo and in vitro.
Additional information: Clone REA908 displays negligible binding to Fc receptors.

Alternative names

CKAP4, Plasma Cell, Climp-63

Detailed product information

Technical specifications

CloneREA908
Clonalitymonoclonal
Isotyperecombinant human IgG1
Hostcell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Specieshuman
AntigenPlasma Cell
Alternative names of antigenCKAP4, Plasma Cell, Climp-63
Molecular mass of antigen [kDa]66
Distribution of antigenepithelial cells, osteoblasts, breast, pancreas, melanoma
Entrez Gene ID10970
RRIDAB_2857382, AB_2857383, AB_2857381

References for Plasma Cell Antibody, anti-human, REAfinity™

Publications

  1. Schweizer, A. et al. (1995) Reassessment of the subcellular localization of p63. J. Cell. Sci. 108: 2477-2485
  2. Klopfenstein, D. R. et al. (1998) A novel direct interaction of endoplasmic reticulum with microtubules. EMBO J. 17(21): 6168-6177