Type of antibody:
Primary antibodies, Recombinant antibodies
recombinant human IgG1

Specifications for Neurofilament Antibody, anti-human/mouse, REAfinity™


Clone REA1127 recognizes the 68 kDa component of the polypeptide subunit of human Neurofilament. Under certain conditions, an additional 200 kDa band could be detected. It is not confirmed, if this is in fact a multimer of the 68 kDa protein.
Neurofilament belongs to the intermediate filament family. Neurofilament is a major component of the neuronal cytoskeleton and a useful marker for distinguishing neurons (which are positive for Neurofilament) from glia. It is found in several neural, neuroendocrine, and endocrine tumors, but also in carcinomas of skin and lung and paragangliomas and adrenal and extra-adrenal pheochromocytomas. REA1127 does not recognize GFAP, keratin, vimentin and desmin or small cell lung carcinoma.
Additional information: Clone REA1127 displays negligible binding to Fc receptors.

Detailed product information

Technical specifications

Isotyperecombinant human IgG1
Hosthuman cell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Specieshuman, mouse
Molecular mass of antigen [kDa]61
Distribution of antigentumor cells, neural cells, lung cancer cells
Entrez Gene ID4747
RRIDAB_2857467, AB_2857468, AB_2857466

Resources for Neurofilament Antibody, anti-human/mouse, REAfinity™


Please follow this
to search for Certificates of Analysis (CoA) by lot number.

References for Neurofilament Antibody, anti-human/mouse, REAfinity™


  1. van Muijen, G. N. et al. (1984) Cytokeratin and neurofilament in lung carcinomas. Am. J. Pathol. 116(3): 363-369
  2. Szaro, B. G. and Strong, M. J. (2010) Post-transcriptional control of neurofilaments: New roles in development, regeneration and neurodegenerative disease. Trends Neurosci. 33(1): 27-37
  3. Wang, H. et al. (2012) Neurofilament proteins in axonal regeneration and neurodegenerative diseases. Neural Regen. Res. 7(8): 620-626

Related products for
Neurofilament Antibody, anti-human/mouse, REAfinity™

1 products available

Seems like you are coming from USA!
Do you want to visit our website in your country?