Clone:
REA893
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
FC
Alternative names:
Pacap

Specifications for MZB1 Antibody, anti-rat, REAfinity™

Overview

Clone REA893 recognizes the rat MZB1 antigen, a marginal zone B- and B1-cell–specific protein. Marginal zone B cells are noncirculating mature B cells, that are located in the spleen. In association with heavy and light chains of IgM MZB1 mediates IgM secretion and assembly. Furthermore, MZB1 functions as a proinflammatory cytokine that is involved in chronic inflammation and in affecting cellular expansion.
Additional information: Clone REA893 displays negligible binding to Fc receptors.

Alternative names

Pacap

Detailed product information

Technical specifications

CloneREA893
Clonalitymonoclonal
Isotyperecombinant human IgG1
Isotype controlREA Control Antibody, human IgG1
Hostcell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Speciesrat
AntigenMZB1
Alternative names of antigenPacap
Molecular mass of antigen [kDa]18
Distribution of antigenB cells, spleen
Entrez Gene ID291675
RRIDAB_2726709, AB_2726789, AB_2726710, AB_2726790, AB_2726711, AB_2726787, AB_2726708, AB_2726788

References for MZB1 Antibody, anti-rat, REAfinity™

Publications

  1. Dammers, P. M. et al. (1999) The origin of marginal zone B cells in the rat. Eur. J. Immunol. 29(5): 1522-1531
  2. Hendricks, J. et al. (2011) Class-switched marginal zone B cells in spleen have relatively low numbers of somatic mutations. Mol. Immunol. 48(6-7): 874-882

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MZB1 Antibody, anti-rat, REAfinity™

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