Clone:
REA813
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
FC, IF, MICS, IHC
Alternative names:
H2-AB1, Abeta, H-2Ab, H2-Ab, I-Abeta, IAb, Ia-2, Ia2, Rmcs1

Specifications for MHC Class II Antibody, anti-mouse, REAfinity™

Overview

Clone REA813 recognizes the MHC class II alloantigens I-Ab, I-Aq, I-Ad, I-Ed, and I-Ek that are expressed by most common inbred mouse strains, for example, C57BL/6, BALB/c, or 129/SvEv 1. MHC class II is expressed on antigen-presenting cells, such as dendritic cells, monocytes/macrophages, B cells in lymphoid and non-lymphoid tissue, thymic epithelial cells, and on subsets of hematopoietic progenitor cells in the bone marrow.
Additional information: Clone REA813 displays negligible binding to Fc receptors.

Alternative names

H2-AB1, Abeta, H-2Ab, H2-Ab, I-Abeta, IAb, Ia-2, Ia2, Rmcs1

Detailed product information

Technical specifications

CloneREA813
Clonalitymonoclonal
Isotyperecombinant human IgG1
Isotype controlREA Control Antibody, human IgG1
Hostcell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Speciesmouse
AntigenMHC Class II
Alternative names of antigenH2-AB1, Abeta, H-2Ab, H2-Ab, I-Abeta, IAb, Ia-2, Ia2, Rmcs1
Molecular mass of antigen [kDa]27
Distribution of antigendendritic cells, macrophages, monocytes, epithelial cells, stem cells, hematopoietic stem and progenitor cells, cancer stem cells
Entrez Gene ID14961
RRIDAB_2652903, AB_2652904, AB_2652905, AB_2652906, AB_2652907, AB_2652908, AB_2652909, AB_2652910, AB_2652911, AB_2652912, AB_2652913, AB_2652914, AB_2652915, AB_2652916, AB_2652917, AB_2652918, AB_2652919, AB_2652920, AB_2652902

References for MHC Class II Antibody, anti-mouse, REAfinity™

Publications

  1. Bhattacharya, A. et al. (1981) A shared alloantigenic determinant on Ia antigens encoded by the I-A and I-E subregions: evidence for I region gene duplication. J. Immunol. 127(6): 2488-2495
  2. Watts, C. (1997) Capture and processing of exogenous antigens for presentation on MHC molecules. Annu. Rev. Immunol. 15: 821-850

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