The MACS
®
GMP PepTivator Melanoma Select is a peptide pool that consists mainly of 15-mer peptides. It has been developed for the efficient in vitro stimulation and subsequent isolation of antigen-specific CD4
+
and CD8
+
T cells.

Specifications for
MACS
®
GMP PepTivator
®
Melanoma Select

Overview

The MACS
®
GMP PepTivator Melanoma Select is a peptide pool that consists mainly of 15-mer peptides. It has been developed for the efficient in vitro stimulation and subsequent isolation of antigen-specific CD4
+
and CD8
+
T cells.

Detailed product information

Background information

The MACS
®
GMP PepTivator Melanoma Select is a peptide pool of 14 lyophilized oligopeptides, consisting of lyophilized MHC class I and class II restricted peptides derived from 5 proteins, commonly expressed by melanoma cells: GP100, MAGEA3, MAGE-C2, NY-ES01 and Tyrosinase. The peptides are restricted for the following HLA-molecules: HLA-A*01, -A*02, -A*03, -A*31, -B*35, -B*44, -C*07, -DR4, -DP4, -DQ6.

Applications

MACS
®
GMP PepTivator Melanoma Select can be used for a variety of applications, for example,
in vitro
stimulation of antigen-specific CD4
+
and CD8
+
T cells for the enrichment of IFN‑gamma–secreting T cells using the CliniMACS
®
Cytokine Capture System (IFN-gamma) (# 279-01).
 

Quality statement

MACS GMP Products are manufactured and tested under a quality management system (ISO 13485) and are in compliance with relevant GMP guidelines. They are designed following the recommendations of USP <1043> on ancillary materials.

Disclaimer

MACS GMP Products are for research use and
ex vivo
cell culture processing only, and are not intended for human
in vivo
applications. For regulatory status in the USA, please contact your local representative.

Resources for
MACS
®
GMP PepTivator
®
Melanoma Select

Certificates

Please follow this
link
to search for Certificates of Analysis (CoA) by lot number.