Clone:
4B4-1
Isotype:
mouse IgG1κ
Alternative names:
TNFRSF9, 4-1BB, CDw137, ILA

Specifications for
MACS
®
GMP CD137 Fluorescent Antibodies

Overview

This antibody recognizes the CD137 (4-1BB) antigen, a 30 kDa glycoprotein of the tumor necrosis factor (TNF) receptor superfamily. CD137 is mainly expressed on activated CD4 and CD8 T cells, activated B cells, and natural killer cells, but can also be found on resting monocytes and dendritic cells. As a costimulatory molecule it is involved in the activation and survival of CD4 or CD8 T cells, and NK cells. CD137 has been described to be a suitable marker for antigen-specific activation of human CD8 T cells, as it is not expressed on resting CD8 T cells and its expression is reliably induced after 24 hours of stimulation.

Alternative names

TNFRSF9, 4-1BB, CDw137, ILA

Detailed product information

Quality statement

MACS GMP Products are manufactured and tested under a quality management system (ISO 13485) and are in compliance with relevant GMP guidelines. They are designed following the recommendations of USP <1043> on ancillary materials.

Disclaimer

MACS GMP Products are for research use and
ex vivo
cell culture processing only, and are not intended for human
in vivo
applications. For regulatory status in the USA, please contact your local representative.