CD45 antibodies, rat

CD45 antibodies, rat

Clone: REA504 | Dilution: 1:50
Clone REA504 recognizes the rat CD45 antigen, also known as leukocyte common antigen (LCA), which is a 180–220 kDa type I transmembrane protein with multiple isoforms and differential glycosylation. It appears in at least five isoforms depending on the differentiation status of the cell. CD45 is expressed at high levels on all cells of hematopoietic origin except for erythrocyte and platelets. It plays a role in signal transduction through B and T cell antigen receptors.
Additional information: Clone REA504 displays negligible binding to Fc receptors.

Alternative names

Ptprc, L-CA, T200

Technical specifications

  • Antigen: CD45
  • Clone: REA504
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control antibodies
  • Alternative names of antigen: Ptprc, L-CA, T200
  • Entrez Gene ID: 24699
  • Molecular mass of antigen [kDa]: 141
  • Distribution of antigen: leukocytes
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: APC-Vio770, Biotin
  • Selected references

    1. Sunderland, C. A. et al. (1979) Purification with monoclonal antibody of a predominant leukocyte-common antigen and glycoprotein from rat thymocytes. Eur. J. Immunol. 9(2): 155-159
    2. Mojcik, D. L. et al. (1987) Monoclonal antibodies to RT7 and LCA antigens in the rat: cell distribution and segregation analysis. Hybridoma 6(5): 531-543
Product options: 3
30 µg in 200 µL (1)
150 µg in 1 mL (1)

CD45-Biotin, rat

30 µg in 200 µL (1)

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