Clone:
REA1022
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
FC
Alternative names:
Klra7, LGL-1, Ly49G.4, Ly49g1, Kira-7, Ly49G2

Specifications for Ly-49G Antibody, anti-mouse, REAfinity™

Overview

Clone REA1022 recognizes the type II transmembrane protein Ly-49G, which is a MHC class I receptor also known as Kira-7. It is expressed on NK, NKT, and T cells. It is reported that the binding of Ly-49G with its ligand leads to inhibition of NK cells, T cells cytotoxicity, cytokine production, and proliferation. The antibody reacts with Ly49G receptor of A/J, BALB/c, C3H, CBA,129, FVB, and SJL mice, but not C57BL/6 mice.
Additional information: Clone REA1022 displays negligible binding to Fc receptors.

Alternative names

Klra7, LGL-1, Ly49G.4, Ly49g1, Kira-7, Ly49G2

Detailed product information

Technical specifications

CloneREA1022
Clonalitymonoclonal
Isotyperecombinant human IgG1
Isotype controlREA Control Antibody, human IgG1
Hostcell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Speciesmouse
AntigenLy-49G
Alternative names of antigenKlra7, LGL-1, Ly49G.4, Ly49g1, Kira-7, Ly49G2
Molecular mass of antigen [kDa]33
Distribution of antigenNK cells, T cells, NKT cells
Entrez Gene ID16638
RRIDAB_2733738, AB_2733483, AB_2733600

References for Ly-49G Antibody, anti-mouse, REAfinity™

Publications

  1. Makrigiannis, A. P. et al. (2004) Independent control of Ly49g alleles: implications for NK cell repertoire selection and tumor cell killing. J. Immunol. 172: 1414-1425
  2. Rouhi, A. et al. (2007) Plasticity of Ly49g expression is due to epigenetics. Mol. Immunol. 44(5): 821-826

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