Clone:
IS11-21E11
Type of antibody:
Primary antibodies
Isotype:
mouse IgG1κ
Applications:
FC, MICS, IF, IHC
Alternative names:
IGHA2

Extended validation for IgA2 Antibody, anti-human

Specificity

Epitope competition
In order to compare the epitope specificity of an antibody, the clone being used is compared with other known clones recognizing the same antigen in a competition assay.
Other clonesOverlap in epitope recognition with IS11-21E11
A9604D2++
REA995++
Cells were incubated with an excess of purified unconjugated IgA2 (IS11-21E11) antibody followed by staining with fluorochrome-conjugated antibodies of other known clones against the same marker. Based on the fluorescence signal obtained, the clones were identified as recognizing completely overlapping (++), partially overlapping (+), or completely different epitopes (-) of the marker.

Specifications for IgA2 Antibody, anti-human

Overview

The Anti-IgA2 antibody, clone IS11-21E11, detects the IgA2 subclass of human immunoglobulin. IgA is present either as monomer or in a secreted form as a multimer of 2–4 molecules, connected by the J-chain and the so-called secretory component. Secreted IgA is transported across epithelial cells and secreted into the lumen of the respiratory and gastrointestinal tract. IgA2 is produced by B cells in the mucosae and is the most abundant immunoglobulin in mucosal secretions.

Alternative names

IGHA2

Detailed product information

Technical specifications

CloneIS11-21E11
Clonalitymonoclonal
Isotypemouse IgG1κ
Isotype controlIsotype Control Antibody, mouse IgG1
Hostmouse
Type of antibodyPrimary antibodies
Specieshuman
AntigenIgA2
Alternative names of antigenIGHA2
Distribution of antigenB cells
Entrez Gene ID3494
RRIDAB_2659759, AB_1036168, AB_1036162, AB_2659760, AB_2659761, AB_2659762, AB_2659763, AB_2659764, AB_2659765, AB_2659766, AB_2659767, AB_2659768, AB_2659769, AB_1036164, AB_1036160, AB_1036166

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