Clone:
REA799
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
ICFC
Alternative names:
Early growth response protein 1, AT225, NGFI-A, KROX24, ZNF225, ZENK, EGR1

Specifications for EGR-1 Antibody, anti-human, REAfinity™

Overview

Clone REA799 recognizes the human transcriptional regulator EGR-1 (early growth response protein 1), also known as ZENK or ZNF225. EGR-1 is a member of the EGR family of Cys2His2-type zinc finger transcription factors. EGR-1 induces the transcription of target genes whose products are important for mitogenesis and differentiation. EGR-1 is found in various types of tissues, e.g. in the brain.
Additional information: Clone REA799 displays negligible binding to Fc receptors.

Alternative names

Early growth response protein 1, AT225, NGFI-A, KROX24, ZNF225, ZENK, EGR1

Detailed product information

Technical specifications

CloneREA799
Clonalitymonoclonal
Isotyperecombinant human IgG1
Isotype controlREA Control Antibody (I), human IgG1
Hostcell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Specieshuman
AntigenEGR-1
Alternative names of antigenEarly growth response protein 1, AT225, NGFI-A, KROX24, ZNF225, ZENK, EGR1
Distribution of antigenother, brain
RRIDAB_2651619, AB_2651620, AB_2651621, AB_2651618

References for EGR-1 Antibody, anti-human, REAfinity™

Publications

  1. Pavletich, N. P. and Pabo, C. O. (1991) Zinc finger-DNA recognition: crystal structure of a Zif268-DNA complex at 2.1 A. Science 252(5007): 809-817
  2. Petersohn, D. et al. (1996) Role of zinc-finger proteins Sp1 and zif268/egr-1 in transcriptional regulation of the human synaptobrevin II gene. Eur. J. Biochem. 239(3): 827-834
  3. Gómez-Martín, D. et al. (2010) Early growth response transcription factors and the modulation of immune response: implications towards autoimmunity. Autoimmun Rev 9(6): 454-458

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