Clone:
REA1230
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
FC, MICS, IF, IHC, MC
Alternative names:
CEACAM1, CEACAM5, CEACAM8, CEACAM6, BGP, CEA, CGM6, NCA, NCA-160

Specifications for CD66abce Antibody, anti-human, REAfinity™

Overview

CD66 constitutes a gene family whose members belong to the family of carcinoembryonic antigens (CEA). They are involved in a wide variety of physiological processes such as embryonic development, pregnancy, bile transport, as well as pathological conditions such as cancer, bacterial or viral infection, and inflammation.
CD66a (CEACAM1), CD66b (CEACAM8), CD66c (CEACAM6), and CD66e (CEACAM5) are differentially expressed on some epithelial cells as well as on T cells, NK cell subsets, and granulocytes, especially neutrophils.
Additional information: Clone REA1230 displays negligible binding to Fc receptors.

Alternative names

CEACAM1, CEACAM5, CEACAM8, CEACAM6, BGP, CEA, CGM6, NCA, NCA-160

Detailed product information

Technical specifications

CloneREA1230
Clonalitymonoclonal
Isotyperecombinant human IgG1
Isotype controlREA Control Antibody (S), human IgG1
Hostcell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Specieshuman
AntigenCD66abce
Alternative names of antigenCEACAM1, CEACAM5, CEACAM8, CEACAM6, BGP, CEA, CGM6, NCA, NCA-160
Molecular mass of antigen [kDa]30-70
Distribution of antigenepithelial cells, T cells, NK cells, neutrophils
Entrez Gene ID634, 1088, 4680, 1048
RRIDAB_2819643, AB_2819652, AB_2819644, AB_2819653, AB_2819645, AB_2819654, AB_2819646, AB_2819655, AB_2819647, AB_2819656, AB_2819648, AB_2819657, AB_2819649, AB_2819658, AB_2819650, AB_2819651

References for CD66abce Antibody, anti-human, REAfinity™

Publications

  1. Gray-Owen, S. D. and Blumberg, R. S. (2006) CEACAM1: contact-dependent control of immunity. Nat. Rev. Immunol. 6: 433-446