Clone:
145/15
Type of antibody:
Primary antibodies
Isotype:
mouse IgG1κ
Applications:
FC, MICS, IF, IHC
Alternative names:
Sell, LAM1, LECAM1, LEU8, Lnhr, LSEL, Lyam1, PLNHR, TQ1, LAM-1

Specifications for CD62L Antibody, anti-human

Overview

Clone 145/15 recognizes the human CD62L antigen, a 74 kDa glycoprotein and a member of the selectin family of cell surface molecules. CD62L is also known as L-selectin, LECAM-1, or LAM-1 and binds a series of glycoproteins including CD34, GlyCAM-1, and MAdCAM-1. CD62L is important for homing of naive lymphocytes via endothelial venules to peripheral lymph nodes and Peyer’s patches. The CD62L antigen also contributes to the recruitment of leukocytes from the blood to areas of inflammation. Most hematopoietic cells express CD62L, including many peripheral blood B cells, T cells, monocytes, granulocytes, and some myeloid cells from bone marrow, and thymocytes. CD62L is continuously endoproteolytically cleaved from the cell surface neutrophils and lymphocytes (shedding). Proteolysis is accelerated, for example, after antigenic activation of T cells.
Always use fresh material for immunofluorescent staining of CD62L
+
cells. For optimal results, the cells should not be older than 8–12 hours. Keep cells continuously cold. CD62L-expression may be rapidly lost due to shedding.

Alternative names

Sell, LAM1, LECAM1, LEU8, Lnhr, LSEL, Lyam1, PLNHR, TQ1, LAM-1

Detailed product information

Technical specifications

Clone145/15
Clonalitymonoclonal
Isotypemouse IgG1κ
Isotype controlIsotype Control Antibody, mouse IgG1
Hostmouse
Type of antibodyPrimary antibodies
Specieshuman
AntigenCD62L
Alternative names of antigenSell, LAM1, LECAM1, LEU8, Lnhr, LSEL, Lyam1, PLNHR, TQ1, LAM-1
Molecular mass of antigen [kDa]38
Distribution of antigenB cells, granulocytes, Langerhans cells, lymphocytes, monocytes, NK cells, red blood cells, T cells, eosinophils, neutrophils, thymocytes, bone marrow, spleen
Entrez Gene ID6402
RRIDAB_2733652, AB_2751216, AB_2751150, AB_2733391, AB_2733392, AB_2751218, AB_2751152, AB_2726469, AB_2726192, AB_2751217, AB_2751151, AB_2751215, AB_2751149, AB_2733651

Reviews for CD62L Antibody, anti-human

Staining Peripheral Blood with Anti-CD62L PE/Vio770

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CD62L-PE-Vio770, human (130-113-621)

Works well. Reproducible results.

Staining Peripheral Blood with Anti-CD62L PE/Vio770

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CD62L-PE-Vio770, human (130-114-147)

Works well. Reproducible results.

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CD62L Antibody, anti-human

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