Clone:
HM48-1
Type of antibody:
Primary antibodies, Functional-grade antibodies
Isotype:
hamster IgG1, hamster IgG1λ
Applications:
FA, FC, MICS, IF, IHC
Alternative names:
BCM1, BLAST, Blast-1, Bcm-1, MEM-102, SLAMF2, Sgp-60, CD48

Specifications for CD48 Antibody, anti-mouse

Overview

The HM48-1 antibody reacts with the CD48 mouse antigen, which is a 45 kDa GPI-linked glycoprotein also known as BCM1, blast-1 (human), or OX-45 (rat). CD48 belongs to the SLAM family including CD48, CD244, and CD150. These cell surface receptors were differentially expressed among functionally progenitors. Hematopoietic stem cells are highly purified as CD150
CD48
CD244
cells, multipotent hematopoietic progenitors are CD244
+
CD150
CD48
and most restricted progenitor cells are CD48
+
CD244
+
CD150
. In mouse, the ligands for CD48 are CD2 and CD244.

Alternative names

BCM1, BLAST, Blast-1, Bcm-1, MEM-102, SLAMF2, Sgp-60, CD48

Detailed product information

Technical specifications

CloneHM48-1
Clonalitymonoclonal
Isotypehamster IgG1, hamster IgG1λ
Hosthamster
Type of antibodyPrimary antibodies, Functional-grade antibodies
Speciesmouse
AntigenCD48
Alternative names of antigenBCM1, BLAST, Blast-1, Bcm-1, MEM-102, SLAMF2, Sgp-60, CD48
Molecular mass of antigen [kDa]22
Distribution of antigenB cells, granulocytes, monocytes, red blood cells, T cells, lymphocytes, leukocytes
Entrez Gene ID12506
RRIDAB_2658414, AB_2658427, AB_2658428, AB_2658429, AB_2658430, AB_2658431, AB_2658432, AB_2658433, AB_2658434

Resources for CD48 Antibody, anti-mouse

Documents and Protocols

References for CD48 Antibody, anti-mouse

Publications

  1. Latchman, Y. et al. (1998) Cutting edge: Identification of the 2B4 molecule as a counter-receptor for CD48. J. Immunol. 161: 5809-5812
  2. Kato, K. et al. (1992) CD48 is a counter-receptor for mouse CD2 and is involved in T cell activation. J. Exp. Med. 176: 1241
  3. Kiel, M.J. et al. (2005) SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells. Cell 121(7): 1109-1121