Clone:
REA639
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
FC

Specifications for CD45RA Antibody, anti-mouse, REAfinity™

Overview

Clone REA639 recognizes the exon A-dependent epitope CD45RA in mouse, one of eight isoforms of the transmembrane glycoprotein CD45, which is a member of the protein tyrosine phosphatase (PTP) family. CD45RA is expressed highly on B cells, weakly on CD8
+
T cells, and nearly on all B cell–lineages but it is not detectable on hematopoietic stem cells or myeloid progenitors.
Additional information: Clone REA639 displays negligible binding to Fc receptors.

Detailed product information

Technical specifications

CloneREA639
Clonalitymonoclonal
Isotyperecombinant human IgG1
Isotype controlREA Control Antibody, human IgG1
Hostcell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Speciesmouse
AntigenCD45RA
Molecular mass of antigen [kDa]135
Distribution of antigenT cells, B cells
Entrez Gene ID19264
RRIDAB_2658322, AB_2658323, AB_2658324, AB_2658325, AB_2658326, AB_2658327, AB_2658328, AB_2658329, AB_2658330, AB_2658331, AB_2658332, AB_2658333, AB_2658334, AB_2658335, AB_2658336, AB_2658337, AB_2784219

References for CD45RA Antibody, anti-mouse, REAfinity™

Publications

  1. Hathcock, K. S. et al. (1992) Expression of variable exon A-, B-, and C-specific CD45 determinants on peripheral and thymic T cell populations. J. Immunol. 148: 19-28
  2. Inoue, T. et al. (1993)
    Distinction of mouse CD8
    +
    suppressor effector T cell clones from cytotoxic T cell clones by cytokine.
    J. Immunol. 150: 2121-2128

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