Clone:
REA840
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
FC, MICS, IF, IHC
Alternative names:
Spn, Leukosialin, GALGP, Ly-48, gpL115, Sialophorin

Specifications for CD43 Antibody, anti-mouse, REAfinity™

Overview

Clone REA840 recognizes the mouse CD43 antigen, a glycosylated protein also known as leukosialin or sialophorin, which is expressed on IL-7–responsive pro–B cells, plasma cells, peritoneal and spleen CD5
+
B cells (B-1 cells), granulocytes, monocytes, macrophages, platelets, NK cells, thymocytes, peripheral cytotoxic T cells, and most T helper cells. CD43 is not expressed on resting conventional peripheral B cells. Thus, resting B cells are easily identified by the lack of CD43 expression.
Additional information: Clone REA840 displays negligible binding to Fc receptors.

Alternative names

Spn, Leukosialin, GALGP, Ly-48, gpL115, Sialophorin

Detailed product information

Technical specifications

CloneREA840
Clonalitymonoclonal
Isotyperecombinant human IgG1
Isotype controlREA Control Antibody, human IgG1
Hostcell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Speciesmouse
AntigenCD43
Alternative names of antigenSpn, Leukosialin, GALGP, Ly-48, gpL115, Sialophorin
Molecular mass of antigen [kDa]38
Distribution of antigenB cells, granulocytes, lymphocytes, macrophages, megakaryocytes, stem cells, monocytes, NK cells, platelets, red blood cells, T cells, basophils, mesenchymal stem cells, neutrophils, plasma cells, thymocytes, bone marrow
Entrez Gene ID20737
RRIDAB_2658115, AB_2658117, AB_2658118, AB_2658119, AB_2658120, AB_2658121, AB_2658123, AB_2658124, AB_2658113

References for CD43 Antibody, anti-mouse, REAfinity™

Publications

  1. Cyster, J. et al. (1990) Protein sequence and gene structure for mouse leukosialin (CD43), a T lymphocyte mucin without introns in the coding sequence. Eur. J. Immunol. 20(4): 875-881
  2. Dorfman, K. S. et al. (1990) The nucleotide sequence of Ly 48 (mouse leukosialin, sialophorin): the mouse homolog of CD43. Nucleic Acids Res. 18(16): 4932-4932
  3. van den Berg, T. K. et al. (2001) Cutting Edge: CD43 functions as a T cell counterreceptor for the macrophage adhesion receptor Sialoadhesin (Siglec-1). J. Immunol. 166(6): 3637-3640

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