Clone:
REA815
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
FC, MICS, IF, IHC
Alternative names:
NCR1, LY94, NK-p46, MAR-1

Specifications for CD335 (NKp46) Antibody, anti-mouse, REAfinity™

Overview

Clone REA815 recognizes the mouse CD335 antigen, also known as NKp46, which is a type I transmembrane protein with two extracellular Ig-like domains. It is a member of the natural cytotoxicity receptor (NCR) family, which triggers cytotoxicity in NK cells. NKp46 is involved in target cell recognition and lysis and seems to be exclusively expressed on NK cells. Staining has been shown on BALB/c, SJL, CBA/CA, C57Bl/6, NOD, DBA/2, and B6.129 mice.
Additional information: Clone REA815 displays negligible binding to Fc receptors.

Alternative names

NCR1, LY94, NK-p46, MAR-1

Detailed product information

Technical specifications

CloneREA815
Clonalitymonoclonal
Isotyperecombinant human IgG1
Isotype controlREA Control Antibody, human IgG1
Hostcell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Speciesmouse
AntigenCD335 (NKp46)
Alternative names of antigenNCR1, LY94, NK-p46, MAR-1
Molecular mass of antigen [kDa]36
Distribution of antigenNK cells
Entrez Gene ID17086
RRIDAB_2657601, AB_2657602, AB_2657603, AB_2657604, AB_2657605, AB_2657606, AB_2657607, AB_2657608, AB_2657609, AB_2657610, AB_2657611, AB_2657612, AB_2657613, AB_2657614, AB_2657615, AB_2657616, AB_2657617, AB_2657600

References for CD335 (NKp46) Antibody, anti-mouse, REAfinity™

Publications

  1. Biassoni, R. et al. (1999) The murine homologue of the human NKp46, a triggering receptor involved in the induction of natural cytotoxicity. Eur. J. Immunol. 29(3): 1014-1020
  2. Walzer, T. et al. (2007)
    Identification, activation, and selective
    in vivo
    ablation of mouse NK cells via NKp46.
    Proc. Natl. Acad. Sci. U.S.A. 104: 3384-3389

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