Clone:
REA1115
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
FC, MICS, IF, IHC
Alternative names:
TNFRSF13c, BR3, BAFFR, BROMIX, CVID4, prolixin, BAFF-R

Specifications for CD268 Antibody, anti-human, REAfinity™

Overview

Clone REA1115 recognizes the human CD268 antigen, also known as B cell–activating factor receptor (BAFF-R), or BAFF receptor 3 (BR3). It is a 19 kDa type III transmembrane protein which belongs to the TNF receptor superfamily and is mainly expressed on B cells. BAFF-R plays an important role in B cell differentiation and promotes survival and activation of B cells.
Additional information: Clone REA1115 displays negligible binding to Fc receptors.

Alternative names

TNFRSF13c, BR3, BAFFR, BROMIX, CVID4, prolixin, BAFF-R

Detailed product information

Technical specifications

CloneREA1115
Clonalitymonoclonal
Isotyperecombinant human IgG1
Isotype controlREA Control Antibody (S), human IgG1
Hostcell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Specieshuman
AntigenCD268
Alternative names of antigenTNFRSF13c, BR3, BAFFR, BROMIX, CVID4, prolixin, BAFF-R
Molecular mass of antigen [kDa]19
Distribution of antigenB cells, T cells
Entrez Gene ID115650
RRIDAB_2751674, AB_2751695, AB_2751675, AB_2751696, AB_2751676, AB_2751697, AB_2751677, AB_2751698, AB_2751678, AB_2751699, AB_2751679, AB_2751700, AB_2751680, AB_2751701, AB_2751681, AB_2751694

References for CD268 Antibody, anti-human, REAfinity™

Publications

  1. Thompson, J. S. et al. (2001) BAFF-R, a newly identified TNF receptor that specifically interacts with BAFF. Science 293(5537): 2108-2111
  2. Kayagaki, N. et al. (2002) BAFF/BLyS receptor 3 binds the B cell survival factor BAFF ligand through a discrete surface loop and promotes processing of NF-κB2. Immunity 17(4): 515-524

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CD268 Antibody, anti-human, REAfinity™

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