Clone:
17B5-1H1
Type of antibody:
Primary antibodies, Functional-grade antibodies
Isotype:
hamster IgG2
Applications:
FC, FA
Alternative names:
TNFRSF9, 4-1BB, CDw137, ILA, Ly63

Specifications for CD137 Antibody, anti-mouse

Overview

Clone 17B5 reacts with mouse CD137, also known as 4-1BB or TNFRSF9, a member of the TNFR superfamily. It is expressed on the cell surface of T cells upon activation. The interaction of CD137 with its ligand, 4-1BBL, on antigen presenting cells (APCs) delivers a bidirectional costimulatory signal. CD137 engagement is shown to be required for CD8
+
T cell survival and memory formation. The monoclonal antibody 17B5 is reported to have strong antagonistic effect in
in vitro
functional assays.

Alternative names

TNFRSF9, 4-1BB, CDw137, ILA, Ly63

Detailed product information

Technical specifications

Clone17B5-1H1
Clonalitymonoclonal
Isotypehamster IgG2
Hosthamster
Type of antibodyPrimary antibodies, Functional-grade antibodies
Speciesmouse
AntigenCD137
Alternative names of antigenTNFRSF9, 4-1BB, CDw137, ILA, Ly63
Molecular mass of antigen [kDa]25
Distribution of antigenB cells, T cells, epithelial cells, fibroblasts, lymphocytes, macrophages, monocytes, dendritic cells
Entrez Gene ID21942
RRIDAB_2654982, AB_2654995, AB_2654996, AB_2654997, AB_2655000, AB_2733199

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