Clone:
293C3
Type of antibody:
Primary antibodies
Isotype:
mouse IgG2b
Alternative names:
PROM1, AC133, CORD12, MCDR2, MSTP061, PROML1, RP41, STGD4

Specifications for CD133/2 antibodies

Overview

CD133 is a 5-transmembrane cell surface antigen with a molecular weight of 117 kDa. It is expressed on a subset of CD34
bright
stem and progenitor cells in human fetal liver, bone marrow, cord blood, and peripheral blood but is not found on mature blood cells¹. Additionally, CD133 is expressed by a small portion of CD34
cells in these tissues.
In contrast to the CD34 antigen, CD133 is not expressed by late progenitors such as pre–B cells, CFU-E, and CFU-G²
,
³.
Clone 293C3 recognizes epitope 2 of the CD133 antigen.

Alternative names

PROM1, AC133, CORD12, MCDR2, MSTP061, PROML1, RP41, STGD4

Detailed product information

Technical specifications

Clone293C3
Isotypemouse IgG2b
Isotype controlIsotype Control Antibody, mouse IgG2b
Type of antibodyPrimary antibodies
Specieshuman
AntigenCD133/2
Alternative names of antigenPROM1, AC133, CORD12, MCDR2, MSTP061, PROML1, RP41, STGD4
Molecular mass of antigen [kDa]117
Distribution of antigenendothelial cells, epithelial cells, red blood cells, ES and iPS cells, hematopoietic stem and progenitor cells
Entrez Gene ID8842

Resources for CD133/2 antibodies

Certificates

Please follow this
link
to download the Certificate of Conformity (CoC) by lot number.

References for CD133/2 antibodies

Publications

  1. Yin, A. H. et al. (1997) AC133, a novel marker for human hematopoietic stem and progenitor cells. Blood 90: 5002-5012
  2. Freund, D. et al. (2006) Comparative analysis of proliferative potential and clonogenicity of MACS-immunomagnetic isolated CD34+ and CD133+ blood stem cells derived from a single donor. Cell Prolif. 39: 325-332
  3. Matsumoto, K. et al. (2000) Stem Cells 24: 2456-2465

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CD133/2 antibodies

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