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Mapping interactions in biological systems requires expanding from methods that look at single cells to finding ways to understand changes within a biological process or population. Whether tracking protein expression, transcription factors or cellular differentiation, multiparameter analysis with flow cytometry will help shed light on the interactions within any cellular system.
The MACSQuant assays for systems biology include:
- Fluorescent protein reporter assays
- Protein interactions (FRET)
- Cell fate tracking with fluorescent proteins
- Enumeration and analysis of cell populations
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