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This issue includes customer reports on:

• Generation of tumor-infiltrating lymphocyte cultures for adoptive therapy
• Clinical-grade purification and expansion of CD56⁺CD3^– NK cells
• T cell activation and expansion with GMP-grade CD3/CD28 antibodies

Read more about:

• Advancements in clinical applications – MACS® GMP Products
• New perspectives for DC-based immune therapy: blood dendritic cells

This issue includes a report by Dr. Michael Watts, University College London, on the evaluation of CryoMACS® Freezing Bags for the cryopreservation of stem cell harvests in clinical transplantation.

Read the reports by our customers:

• Clinical-grade manufacturing of autologous mature RNA electroporated dendritic cells from CD14⁺ monocytes of acute myeloid leukemia patients in remission
• T cell and B cell depletion in an allogeneic stem cell transplantation setting by employing CD3⁺/CD19⁺ cell depletion and enrichment of CD34⁺ cells

This issue includes customer reports on:

• Cord blood transplantation for adults supported by co-infusion of selected CD34⁺ hematopoietic stem cells from third party donors
• Depletion of CD8-positive T cells from donor leukaphereses in a GMP procedure