Research areas - Neuroscience - Cell separation - Neural cell isolation

Experience fast, simple, and reliable neural cell isolation

Neural cells are typically very sensitive cells, and it is therefore important, not only to use techniques, which are very gentle, but also techniques which reduce any manipulation time to a minimum. MACS® Technology is both gentle and quick and so ideally suited for neural cell populations.

A wide and expanding range of MicroBeads and kits allows the direct isolation of different neural cell types, including:

  • Neurons
  • Astrocytes
  • Microglia
  • Oligodendrocytes and precursors
  • Endothelial cells
  • Neural stem cells
  • Neuronal progenitors 
  • Glial progenitors

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Neurons

Retinal ganglion cells and neuronal committed precursor cells can be isolated with ease using either the Retinal Ganglion Cell Isolation Kit or the Anti-PSA-NCAM MicroBeads, respectively. Discover the benefits first hand by reading a related customer report, entitled: Purification of neuronal precursors.

Astrocytes

Now, for the first time, astrocytes can be directly isolated according to their expression of GLAST. Anti-GLAST (ACSA-1) MicroBeads are based on the first antibody developed specifically for an extracellular epitope of the astrocyte transmembrane glycoprotein GLAST, and are used for the direct isolation of GLAST-expressing astrocytes.

Advantages are:

  • GLAST is a specific cell surface marker for astrocyte identification and isolation
  • Direct isolation of astrocytes within less than one hour
  • High purity, minimizing contamination by other cells

Discover more:

  • Get your quotation and directly isolate astrocytes in just 1 hour with the Anti-GLAST (ACSA-1) MicroBead Kit.
  • Watch a movie demonstrating the convenience of Anti-GLAST (ACSA-1) MicroBeads.
  • Download a two-page flyer summarizing our Anti-GLAST products.
  • Read a customer report and scientific poster on the proteomic identification of novel astrocyte cell surface markers.
  • Download abstracts presented at the 2010 SfN that report on the rapid isolation of neural cell populations including astrocytes.
  • Read our scientific poster presented at FENS 2010: “Magnetic isolation of astrocytes using a new GLAST-specific monoclonal antibody.”
  • Watch this hands-on video for the isolation of adult astrocytes from mouse brain tissue.
  • Download the list of materials required for the isolation, analysis, and culture of astrocytes from adult mouse brain

Microglia

Microglia can be efficiently isolated using CD11b (Microglia) MicroBeads. CD11b is widely used as a marker for the identification of microglia and is suitable for their immunomagnetic isolation from mouse or human brain.

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Oligodendrocytes

View our range of MicroBeads available for oligodendrocyte isolation, from precursors to immature oligodendrocytes. Oligodendrocyte precursors can be efficiently isolated using AN2 MicroBeads, glial-restricted precursor cells according to their expression of A2B5 using Anti-A2B5 MicroBeads, and immature oligodendrocytes using O4 MicroBeads. Achieve a Schwann cell purity of around 95% in only a couple of hours using CD271 MicroBead Kits.

Discover more:

Neural progenitors

Profit from MACS® Technology for the effective and rapid isolation of mouse and human neural progenitors. For further information that demonstrates this, simply download a customer’s report on the isolation of a CD133+ tumor-initiating cell subpopulation from human glioblastoma samples.
Find products in Neural cell isolation
34 products available
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Product Order no. Price

Anti-A2B5 MicroBeads, human, mouse, rat

Capacity: for 5×108 total cells
 
130-093-388 $445.00

Anti-A2B5 MicroBeads, human, mouse, rat – small size

Capacity: for 5×107 total cells
 
130-093-392 $75.00

Anti-ABCG2 (CD338) MicroBeads, human

Capacity: for up to 1×109 total cells
 
130-107-680 $550.00

Anti-ACSA-2 MicroBead Kit, mouse

Capacity: for 1×109 total cells
 
130-097-678 $585.00

Anti-ACSA-2 MicroBead Kit, mouse – small size

Capacity: for 5×107 total cells
 
130-097-679 $75.00

Anti-AN2 MicroBeads, human and mouse

Capacity: for 1×109 total cells
 
130-097-170 $500.00

Anti-AN2 MicroBeads, human and mouse – small size

Capacity: for 1×108 total cells
 
130-097-171 $75.00

Anti-GLAST (ACSA-1) MicroBead Kit, human, mouse, rat

Capacity: for 5×108 total cells
 
130-095-826 $460.00

Anti-GLAST (ACSA-1) MicroBead Kit, human, mouse, rat – small size

Capacity: for 5×107 total cells
 
130-095-825 $75.00

Anti-O4 MicroBeads, human, mouse, rat

Capacity: for 1×109 total cells
 
130-094-543 $460.00
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Showing 1-10 of 34


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