Research areas - Immunology - Autoimmunity - Type I diabetes

Type I diabetes

Type I diabetes mellitus results from the autoimmune destruction of insulin-producing beta cells of the pancreas. Therefore, patients can no longer maintain physiological blood glucose levels. Separate and analyze immune cell subsets involved in diabetes using Miltenyi Biotec’s range of cell separation and analysis products.

Download a list of selected references on diabetes research.

Cell separation

To study the role of distinct immune cell types in type I diabetes onset and progression, it is crucial to use pure cell populations. MACS Cell Separation reagents allow for the quick and convenient isolation of the desired cell type, e.g., T cells or B cells. Cells can be isolated from various tissues as well as whole blood.

Cell analysis

Benefit from Miltenyi Biotec’s large portfolio of fluorochrome-conjugated antibodies for human, murine, non-human primate, and rat immune cells to visualize disease-related changes in cell populations. Try our bright fluorochrome-conjugated antibodies for the analysis of T cell subsets, such as islet-autoreactive CD8+ T cells, which play a key role in autoimmune diabetes.
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3104 products available
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autoMACS Pro Separator - Starter Kit

Components:
  • autoMACS Pro Separator Instrument
  • MACS MiniSampler
  • MACS Reagent Rack 4 (130-094-574)
  • Chill 5, 15, 50 Rack Set (130-097-038)
  • barcode reader
  • software
  • autoMACS® Columns (130-021-101)
  • 4×column substitute
  • autoMACS Pro Buffer Combination
  • User manual
  • short instructions
  • one-year warranty
 
130-092-545 price on request here

MACSQuant Analyzer 10

Content: 1 unit
 
130-096-343 price on request here

MACSQuant VYB

Content: 1 unit
 
130-096-116 price on request here

MultiMACS Cell24 Separator Plus

Components:
  • MultiMACS Cell24 Separator
  • MACS Elution Station
  • Elution Chamber Base
  • Elution Chamber Lid I
  • Elution Chamber Lid II
  • Multi-24 Column Block (130-095-692)
  • 2×24-well Deep Well Plate
  • Single-Column Adapter
  • MultiMACS 5 mL Tube Rack (130-095-331)
  • Column Blank Holder and 9 Column Blanks
  • Tubing
  • Power cord
  • Null modem cable
  • High power CAN cable
 
130-098-637 price on request here

21 CFR Part 11 compliant MACSQuantify V2.10 additional PC license

130-112-559 price on request here

21 CFR Part 11 compliant setup of MACSQuantify V2.10

160-002-148 price on request here

24-well Deep Well Plates

Content: 4 pieces (1)

Packing unit

(1)sterile packaged
 
130-110-500 $45.00

Adipose Tissue Progenitor Isolation Kit, mouse

Capacity: for up to 1×108 total cells
 
130-106-639 $435.00

Annexin V MicroBead Kit

Capacity: for 1×109 total cells
 
130-090-201 $700.00

Anti-ABCG2 (CD338) MicroBeads, human

Capacity: for up to 1×109 total cells
 
130-107-680 $550.00
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