Research areas - Immunology - Autoimmunity - Systemic lupus erythematosus

Systemic lupus erythematosus

Systemic lupus erythematosus (SLE) is an incurable autoimmune disease of not yet fully understood etiology. Organs potentially affected include heart, joints, skin, liver, kidneys, and the nervous system. SLE is characterized by circulating IgG autoantibodies that are specific for self-antigen, e.g., DNA, nuclear proteins, and certain cytoplasmic constituents.

Download a list of selected references on SLE research.

Sample preparation

Generate single-cell suspensions from SLE-affected organs using the gentleMACS Dissociators and the appropriate Tissue Dissociation Kits. Optimal sample preparation with a maximum yield of viable cells are the perfect start for your experiment.

Cell separation

Isolate any cell type involved in disease onset and progression by using the most comprehensive cell separation portfolio available. Use the isolated cells immediately in your downstream experiments, such as in vitro assays or phenotypic analysis.

Cell analysis

Improve the phenotypic analysis of the cells of your interest using Miltenyi Biotec’s antibodies. Analyze viable inflammatory cytokine-secreting cells, such as Th17 or Th1 cells using the corresponding Cytokine Secretion Assay – Detection Kits.
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autoMACS Pro Separator - Starter Kit

Components:
  • autoMACS Pro Separator Instrument
  • MACS MiniSampler
  • MACS Reagent Rack 4 (130-094-574)
  • Chill 5, 15, 50 Rack Set (130-097-038)
  • barcode reader
  • software
  • autoMACS® Columns (130-021-101)
  • 4×column substitute
  • autoMACS Pro Buffer Combination
  • User manual
  • short instructions
  • one-year warranty
 
130-092-545 price on request here

MACSQuant Analyzer 10

Content: 1 unit
 
130-096-343 price on request here

MACSQuant VYB

Content: 1 unit
 
130-096-116 price on request here

MultiMACS Cell24 Separator Plus

Components:
  • MultiMACS Cell24 Separator
  • MACS Elution Station
  • Elution Chamber Base
  • Elution Chamber Lid I
  • Elution Chamber Lid II
  • Multi-24 Column Block (130-095-692)
  • 2×24-well Deep Well Plate
  • Single-Column Adapter
  • MultiMACS 5 mL Tube Rack (130-095-331)
  • Column Blank Holder and 9 Column Blanks
  • Tubing
  • Power cord
  • Null modem cable
  • High power CAN cable
 
130-098-637 price on request here

21 CFR Part 11 compliant MACSQuantify V2.10 additional PC license

130-112-559 price on request here

21 CFR Part 11 compliant setup of MACSQuantify V2.10

160-002-148 price on request here

24-well Deep Well Plates

Content: 4 pieces (1)

Packing unit

(1)sterile packaged
 
130-110-500 $45.00

Adipose Tissue Progenitor Isolation Kit, mouse

Capacity: for up to 1×108 total cells
 
130-106-639 $435.00

Annexin V MicroBead Kit

Capacity: for 1×109 total cells
 
130-090-201 $700.00

Anti-ABCG2 (CD338) MicroBeads, human

Capacity: for up to 1×109 total cells
 
130-107-680 $550.00
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