Research areas - Cancer research - Tumor immunology - Cell analysis - Anti-BP-1 (Ly-51) antibodies, mouse

Anti-BP-1 (Ly-51) antibodies, mouse (clone: 6C3)

Overview

The 6C3 monoclonal antibody recognizes mouse Anti-BP-1 (Ly-51), a 140 kDa transmembrane protein. It is expressed on thymic dendritic cells, cortical epithelial cells, and pre B cells and can be upregulated in the presence of IL-7. It has been identified to be an enzyme with aminopeptidase A (APA) activity, so a wide variety of mouse tissue cells which possess APA activity express BP-1 (Ly-51).

Technical data


Antigen BP-1 (Ly-51)
Clone 6C3
Isotype rat IgG2aκ
Isotype control Rat IgG2a – isotype control antibodies
Alternative names of antigen ENPEP, APA, Bp-1/6C3, Ly-51
Entrez Gene ID 13809
Molecular mass of antigen [kDa] 108
Cross-reactivity
Distribution of antigen
Endotoxin level
Product format Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
Fixation Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
Storage Store protected from light at 2–8 °C. Do not freeze.
Available conjugates FITC, PE, APC, Biotin

Gallery

Figure 1

Bone marrow cells from C57BL/6 mouse were stained with Anti-BP-1 (Ly-51) antibodies as well as with CD45R (B220)-VioBlue and analyzed by flow cytometry using the MACSQuant® Analyzer. Cell debris and dead cells were excluded from the analysis based on scatter signals and propidium iodide fluorescence.

Related Items

Library

Selected references

  1. Wu, Q. et al. (1989) The early B lineage antigen BP-1 and the transformation-associated antigen 6C3 are on the same molecule. J. Immunol. 10(143): 3303–3308.
  2. Morse, H. C. et al. (1987) Expression of the 6C3 antigen on murine hematopoietic neoplasms. Association with expression of abl, ras, fes, src, erbB, and Cas NS-1 oncogenes but not with myc. J. Exp. Med.(165): 920.
  3. Pillemer, E. et al. (1984) Transformation-associated proteins in murine B-cell lymphomas that are distinct from Abelson virus gene products. Proc. Natl. Acad. Sci. U.S.A.(81): 4434–4438.

Product Order no. Price

Anti-BP-1 (Ly-51)-FITC, mouse (clone: 6C3)

For research use only
Content: 30 µg in 1 mL (1)

Quantity

(1)200 tests. One test corresponds to labeling of up to 106 cells in a final volume of 50 µL.
 
Data sheet
130-102-170 $40.00

Anti-BP-1 (Ly-51)-PE, mouse (clone: 6C3)

For research use only
Content: 30 µg in 1 mL (1)

Quantity

(1)200 tests. One test corresponds to labeling of up to 106 cells in a final volume of 50 µL.
 
Data sheet
130-102-190 $50.00

Anti-BP-1 (Ly-51)-APC, mouse (clone: 6C3)

For research use only
Content: 30 µg in 1 mL (1)

Quantity

(1)200 tests. One test corresponds to labeling of up to 106 cells in a final volume of 50 µL.
 
Data sheet
130-102-181 $80.00

Anti-BP-1 (Ly-51)-Biotin, mouse (clone: 6C3)

For research use only
Content: 30 µg in 1 mL (1)

Quantity

(1)200 tests. One test corresponds to labeling of up to 106 cells in a final volume of 50 µL.
 
Data sheet
130-101-844 $50.00

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Miltenyi Biotec Inc.
Phone: +1 800 FOR MACS
Fax:+1 877 591 1060
macs@miltenyibiotec.com
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