ExiTron nano 12000 is an alkaline earth metal-based nanoparticulate contrast agent specifically formulated for preclinical computed tomography (CT).
It shows strong X-ray absorption due to the high metal load of the particles.
Upon intravenous injection, ExiTron nano 12000 circulates in the blood stream for a prolonged time. It accumulates in the liver and spleen due to uptake by Kupffer cells (macrophages of the liver).
ExiTron nano 12000 is indicated for use in CT of small animals, for example mice, to facilitate the visualization of the vasculature.
Examples include contrast-enhanced angiography.
Schematic diagram of an ExiTron nano 12000 nanoparticle.