Products and Services - MACS Flow Cytometry - Antibodies - Primary antibodies - CD158e (KIR3DL1) antibodies, human

CD158e (KIR3DL1) antibodies, human (clone: DX9)

Overview

Clone DX9 recognizes CD158e (KIR3DL1), a member of the killer immunoglobulin-like receptor (KIR) family expressed on CD56dimCD16+ natural killer (NK) cells and CD8+ T cells. KIRs contribute to the regulation of NK cell-mediated cytotoxicity. They are monomeric receptors possessing high allelic polymorphism with either 2 or 3 Ig-like extracellular domains. According to the length of their cytoplasmic tail, KIRs can be further subdivided into inhibitory KIRs and activating KIRs (KIR2DS or KIR3DS). KIR3DL1 provides an inhibitory signal of NK cell lytic activity upon interaction with its specific ligand, HLA-Bw4.

Technical data


Antigen CD158e (KIR3DL1)
Clone DX9
Isotype mouse IgG1κ
Isotype control Mouse IgG1 – isotype control antibodies
Alternative names of antigen KIR3DL1, NKB1, NKB1B, p70
Entrez Gene ID 3811
Molecular mass of antigen [kDa] 47
Cross-reactivity
Distribution of antigen NK cells, T cells
Endotoxin level
Product format Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
Fixation Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
Storage Store protected from light at 2–8 °C. Do not freeze.
Available conjugates FITC, PE, APC, VioBlue, VioGreen, PerCP, PE-Vio770, Biotin, pure

Gallery

Figure 1

Human peripheral blood mononuclear cells (PBMCs) were stained with CD158e (KIR3DL1) antibodies as well as with CD56 antibodies and analyzed by flow cytometry using the MACSQuant® Analyzer. The Tandem Signal Enhancer has been used to increase binding specificity of tandem-dye–conjugated antibodies. Cell debris and dead cells were excluded from the analysis based on scatter signals and propidium iodide fluorescence or 4',6-diamidino-2-phenylindole (DAPI) fluorescence, as in the case of tandems.

Related Items

Library

Selected references

  1. Farag, S. S. et al. (2002) Natural killer cell receptors: new biology and insights into the graft-versus-leukaemia effect. Blood 100(6): 1935–1947.
  2. Djeu, J. et al. (2002) A view to a kill: signals triggering cytotoxicity. Clin. Cancer Res. 8: 636–640.
  3. Hsu, K. et al. (2002) The killer cell immunoglobin-like (KIR) genomic region: gene-order, haplotypes and allelic polymorphism. Immunol. Rev. 190: 40–52.
  4. Selvakumar, A. et al. (1997) Polymorphism and domain variability of human killer cell inhibitory receptors. Immunol. Rev. 155: 183–196.

Product Order no. Price

CD158e (KIR3DL1)-FITC, human (clone: DX9)

For research use only
Capacity: for 30 tests (1)

Capacity

(1)One test corresponds to labeling of up to 107 cells in a total volume of 100 µL.
 
Data sheet
130-099-387 price on request here

CD158e (KIR3DL1)-FITC, human (clone: DX9)

For research use only
Capacity: for 100 tests (1)

Capacity

(1)One test corresponds to labeling of up to 107 cells in a total volume of 100 µL.
 
Data sheet
130-092-568 price on request here

CD158e (KIR3DL1)-PE, human (clone: DX9)

For research use only
Capacity: for 100 tests (1)

Capacity

(1)One test corresponds to labeling of up to 107 cells in a total volume of 100 µL.
 
Data sheet
130-092-473 price on request here

CD158e (KIR3DL1)-APC, human (clone: DX9)

For research use only
Capacity: for 30 tests (1)

Capacity

(1)One test corresponds to labeling of up to 107 cells in a total volume of 100 µL.
 
Data sheet
130-099-839 price on request here

CD158e (KIR3DL1)-APC, human (clone: DX9)

For research use only
Capacity: for 100 tests (1)

Capacity

(1)One test corresponds to labeling of up to 107 cells in a total volume of 100 µL.
 
Data sheet
130-092-474 price on request here

CD158e (KIR3DL1)-VioBlue, human (clone: DX9)

For research use only
Capacity: for 30 tests (1)

Capacity

(1)One test corresponds to labeling of up to 107 cells in a total volume of 100 µL.
 
Data sheet
130-099-693 price on request here

CD158e (KIR3DL1)-VioBlue, human (clone: DX9)

For research use only
Capacity: for 100 tests (1)

Capacity

(1)One test corresponds to labeling of up to 107 cells in a total volume of 100 µL.
 
Data sheet
130-095-234 price on request here

CD158e (KIR3DL1)-VioGreen, human (clone: DX9)

For research use only
Capacity: for 30 tests
 
Data sheet
130-108-374 price on request here

CD158e (KIR3DL1)-VioGreen, human (clone: DX9)

For research use only
Capacity: for 100 tests
 
Data sheet
130-108-343 price on request here

CD158e (KIR3DL1)-PerCP, human (clone: DX9)

For research use only
Capacity: for 100 tests (1)

Capacity

(1)One test corresponds to labeling of up to 107 cells in a total volume of 100 µL.
 
Data sheet
130-095-287 price on request here

CD158e (KIR3DL1)-PE-Vio770, human (clone: DX9)

For research use only
Capacity: for 30 tests (1)

Capacity

(1)One test corresponds to labeling of up to 107 cells in a total volume of 100 µL.
 
Data sheet
130-099-960 price on request here

CD158e (KIR3DL1)-PE-Vio770, human (clone: DX9)

For research use only
Capacity: for 100 tests (1)

Capacity

(1)One test corresponds to labeling of up to 107 cells in a total volume of 100 µL.
 
Data sheet
130-099-959 price on request here

CD158e (KIR3DL1)-Biotin, human (clone: DX9)

For research use only
Capacity: for 100 tests (1)

Capacity

(1)One test corresponds to labeling of up to 107 cells in a total volume of 100 µL.
 
Data sheet
130-092-475 price on request here

CD158e (KIR3DL1) pure, human (clone: DX9)

For research use only
Content: 100 µg in 1 mL
 
Data sheet
130-092-555 price on request here


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Miltenyi Biotec Inc.
Phone: +1 800 FOR MACS
Fax:+1 877 591 1060
macs@miltenyibiotec.com
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