Products and Services - MACS Flow Cytometry - Antibodies - Primary antibodies - CD158a/h (KIR2DL1/DS1) antibodies, human

CD158a/h (KIR2DL1/DS1) antibodies, human (clone: 11PB6)

Overview

Clone 11PB6, also referred to as EB6, recognizes CD158a (KIR2DL1) and CD158h (KIR2DS1), two members of the killer immunoglobulin-like receptor (KIR) family expressed on CD56dimCD16+ natural killer (NK) cells and CD8+ T cells.
Recent findings also showed reactivity of 11PB6 with KIR2DL3*005.1
CD158a (KIR2DL1) is involved in the transduction of an inhibitory signal whereas CD158h (KIR2DS1) is an activating receptor. The ligands of CD158a (KIR2DL1) are HLA-Cw4 and related molecules.

Technical data


Antigen CD158a/h (KIR2DL1/DS1)
Clone 11PB6
Isotype mouse IgG1κ
Isotype control Mouse IgG1 – isotype control antibodies
Alternative names of antigen KIR2DL1, KIR-K64, KIR221, NKAT, NKAT-1, p58.1, KIR2DS1
Entrez Gene ID 3802
Molecular mass of antigen [kDa] 36
Cross-reactivity
Distribution of antigen NK cells
Endotoxin level
Product format Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
Fixation The antibody is suited for staining of formaldehyde-fixed cells.
Storage Store protected from light at 2–8 °C. Do not freeze.
Available conjugates FITC, PE, APC, VioBlue, PE-Vio770, Biotin, pure

Gallery

Figure 1

Human peripheral blood mononuclear cells (PBMCs) were stained with CD158a/h (KIR2DL1/DS1) antibodies as well as with CD56 antibodies and analyzed by flow cytometry using the MACSQuant® Analyzer. The Tandem Signal Enhancer has been used to increase binding specificity of tandem-dye–conjugated antibodies. Cell debris and dead cells were excluded from the analysis based on scatter signals and propidium iodide fluorescence or 4',6-diamidino-2-phenylindole (DAPI) fluorescence, as in the case of tandems.

Related Items

Library

Selected references

  1. Falco, M. et al. (2010) Combined genotypic and phenotypic killer cell Ig-like receptor analyses reveal KIR2DL3 alleles displaying unexpected monoclonal antibody reactivity: identification of the amino acid residues critical for staining. J. Immunol. 185: 433–441.

Product Order no. Price

CD158a/h (KIR2DL1/DS1)-FITC, human (clone: 11PB6)

For research use only
Capacity: for 30 tests (1)

Capacity

(1)One test corresponds to labeling of up to 107 cells in a total volume of 100 µL.
 
Data sheet
130-099-194 $80.00

CD158a/h (KIR2DL1/DS1)-FITC, human (clone: 11PB6)

For research use only
Capacity: for 100 tests (1)

Capacity

(1)One test corresponds to labeling of up to 107 cells in a total volume of 100 µL.
 
Data sheet
130-092-811 $225.00

CD158a/h (KIR2DL1/DS1)-PE, human (clone: 11PB6)

For research use only
Capacity: for 30 tests (1)

Capacity

(1)One test corresponds to labeling of up to 107 cells in a total volume of 100 µL.
 
Data sheet
130-099-209 $95.00

CD158a/h (KIR2DL1/DS1)-PE, human (clone: 11PB6)

For research use only
Capacity: for 100 tests (1)

Capacity

(1)One test corresponds to labeling of up to 107 cells in a total volume of 100 µL.
 
Data sheet
130-092-684 $265.00

CD158a/h (KIR2DL1/DS1)-APC, human (clone: 11PB6)

For research use only
Capacity: for 30 tests (1)

Capacity

(1)One test corresponds to labeling of up to 107 cells in a total volume of 100 µL.
 
Data sheet
130-099-715 $120.00

CD158a/h (KIR2DL1/DS1)-APC, human (clone: 11PB6)

For research use only
Capacity: for 100 tests (1)

Capacity

(1)One test corresponds to labeling of up to 107 cells in a total volume of 100 µL.
 
Data sheet
130-092-685 $280.00

CD158a/h (KIR2DL1/DS1)-VioBlue, human (clone: 11PB6)

For research use only
Capacity: for 100 tests (1)

Capacity

(1)One test corresponds to labeling of up to 107 cells in a total volume of 100 µL.
 
Data sheet
130-095-233 $280.00

CD158a/h (KIR2DL1/DS1)-PE-Vio770, human (clone: 11PB6)

For research use only
Capacity: for 30 tests (1)

Capacity

(1)One test corresponds to labeling of up to 107 cells in a total volume of 100 µL.
 
Data sheet
130-099-894 $135.00

CD158a/h (KIR2DL1/DS1)-PE-Vio770, human (clone: 11PB6)

For research use only
Capacity: for 100 tests (1)

Capacity

(1)One test corresponds to labeling of up to 107 cells in a total volume of 100 µL.
 
Data sheet
130-099-891 $290.00

CD158a/h (KIR2DL1/DS1)-Biotin, human (clone: 11PB6)

For research use only
Capacity: for 100 tests (1)

Capacity

(1)One test corresponds to labeling of up to 107 cells in a total volume of 100 µL.
 
Data sheet
130-092-683 $225.00

CD158a/h (KIR2DL1/DS1) pure, human (clone: 11PB6)

For research use only
Content: 100 µg in 1 mL
 
Data sheet
130-092-682 $135.00


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