Products and Services - MACS Cell Culture and Stimulation - Stimulation reagents - Functional-grade antibodies - Anti-HLA-G antibodies - functional grade, human

Anti-HLA-G antibodies - functional grade, human (clone: 87G)

Overview

Clone 87G recognizes the human HLA-G antigen, a heterodimeric class I molecule consisting of a heavy chain and a light chain.The heavy chain is approximately 45 kDa and is anchored in the membrane. HLA-G is expressed on fetal derived placental cells. Clone 87G reacts with isoforms of HLA-G1 and HLA-G5.

Applications

This pure - functional grade antibody is suited for cell culture functional assays, for example, blocking of receptor-ligand binding.

Technical data


Antigen HLA-G
Clone 87G
Isotype mouse IgG2aκ
Isotype control
Alternative names of antigen HLA G antigen, MHC class I antigen G
Entrez Gene ID 3135
Molecular mass of antigen [kDa] 36
Cross-reactivity
Distribution of antigen placenta
Endotoxin level
Endotoxin levels have been tested and do not exceed 0.01 ng/µg of protein.
Product format Antibodies are supplied in phosphate-buffered saline (PBS), pH 7.2. The product contains no preservative and is sterile filtered. Always handle under aseptic conditions.
Fixation
Storage Store protected from light at 2–8 °C. Do not freeze.
Available conjugates pure

Related Items

Library

Selected references

  1. Odum, N. et al. (1991) Homotypic aggregation of human cell lines by HLA class II-, class Ia- and HLA-G-specific monoclonal antibodies. Eur. J. Immunol. 21(9): 2121–2131.
  2. Rutten, M. J. et al. (2014) HLA-G expression is an independent predictor for improved survival in high grade ovarian carcinomas. J Immunol Res.
  3. Jiang, F. et al. (2015) Role of HLA-G1 in trophoblast cell proliferation, adhesion and invasion. Biochem. Biophys. Res. Commun. 458(1): 154–160.

Product Order no. Price

Anti-HLA-G pure – functional grade, human (clone: 87G)

For research use only
Content: 500 µg in 0.5 mL
 
Data sheet
130-111-848 $335.00

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Miltenyi Biotec Inc.
Phone: +1 800 FOR MACS
Fax:+1 877 591 1060
macs@miltenyibiotec.com
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