Products and Services - MACS Cell Culture and Stimulation - Stimulation reagents - Functional grade antibodies - Anti-GM-CSF antibodies – functional grade, human

Anti-GM-CSF antibodies – functional grade, human (clone: BVD2-21C11)

Overview

Granulocyte macrophage colony-stimulating factor (GM‑CSF) is a hematopoietic growth factor that is essential for proliferation and development of granulocyte and monocyte/macrophage progenitors. It also functions as a growth factor for erythroid and megakaryocytic precursor cells in conjunction with erythropoietin. GM-CSF is secreted by various cell types including T cells, macrophages, endothelial cells, and fibroblasts in response to inflammatory stimuli and cytokines. In addition, GM-CSF strongly chemoattracts neutrophils and eosinophils and enhances the effector functions of neutrophils and macrophages.

Applications

This pure - functional grade antibody is suited for functional assays, for example, neutralization of cytokine activity.

Technical data


Antigen GM-CSF
Clone BVD2-21C11
Isotype rat IgG2aκ
Isotype control
Alternative names of antigen CSF2, GM-CSF
Entrez Gene ID 1437
Molecular mass of antigen [kDa] 14
Cross-reactivity rhesus monkey (Macaca mulatta), cynomolgus monkey (Macaca fascicularis)
Distribution of antigen
Endotoxin level
Endotoxin levels have been tested and do not exceed 0.01 ng/µg of protein.
Product format Antibodies are supplied in phosphate-buffered saline (PBS), pH 7.2. The product contains no preservative and is sterile filtered. Always handle under aseptic conditions.
Fixation
Storage Store protected from light at 2–8 °C. Do not freeze.
Available conjugates pure

Related Items

Product Order no. Price

Anti-GM-CSF pure – functional grade, human (clone: BVD2-21C11)

For research use only
Content: 500 µg in 0.5 mL
 
Data sheet
130-096-075 $340.00

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Miltenyi Biotec Inc.
Phone: +1 800 FOR MACS
Fax:+1 877 591 1060
macs@miltenyibiotec.com
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