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Anti-FR4 antibodies – functional grade, mouse (clone: TH6)

Overview

The mouse Anti-FR4 antibody, clone TH6, binds to folate receptor 4 (FR4), a cell surface receptor for folic acid (vitamin B9). FR4 is constitutively expressed at high levels on mouse CD4+CD25+ natural regulatory T (Treg) cells. The high expression of this marker in combination with CD4 and CD25 allows the distinction between Treg cells and other types of T cells.

Applications

The Anti-FR4 pure – functional grade antibody is reported to abrogate regulatory T cell function in vivo.

Technical data


Antigen FR4
Clone TH6
Isotype rat IgG2bκ
Isotype control
Alternative names of antigen IZUMO1R, Folbp3, Folr4, Juno
Entrez Gene ID 64931
Molecular mass of antigen [kDa] 26
Cross-reactivity
Distribution of antigen
Endotoxin level
Endotoxin levels have been tested and do not exceed 0.01 ng/µg of protein.
Product format Antibodies are supplied in phosphate-buffered saline (PBS), pH 7.2. The product contains no preservative and is sterile filtered. Always handle under aseptic conditions.
Fixation
Storage Store protected from light at 2–8 °C. Do not freeze.
Available conjugates pure

Related Items

Product Order no. Price

Anti-FR4 pure – functional grade, mouse (clone: TH6)

For research use only
Content: 1 mg in 0.5 mL
 
Data sheet
130-095-244 price on request here

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Miltenyi Biotec Inc.
Phone: +1 800 FOR MACS
Fax:+1 877 591 1060
macs@miltenyibiotec.com
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