Clinical applications - Immunotherapy - Mesenchymal stem cells

Mesenchymal stem cells

  • Enrichment of well-defined mesenchymal stem cells for pre-clinical and clinical investigations
  • CD271+ cells are highly enriched for CFU-F activity
  • Cells can be directly used or culture expanded for further applications
  • Antibody cross-reactivity shown in large animal
In general, mesenchymal stem cells (MSC) have been investigated in a variety of clinical trials for the treatment of graft-versus-host disease and tissue regeneration. The antigen CD271 is expressed on MSC and can be used for the enrichment of these cells. The characterization of CD271+ cells revealed that the colony-forming-unit fibroblast (CFU-F) potential is highly and exclusively enriched in the CD271+ cell fraction after enrichment using the CliniMACS® Plus System. Following this strategy a well-defined cell population can be used either directly or culture expanded for pre-clinical and clinical investigations. In addition, the cross-reactivity of the antibody shown in large animals allows for an easy translation of pre-clinical investigations into the clinical area.
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CliniMACS Anti-Biotin MicroBeads

Regulatory status: For research use only, not for use in humans
Availability: worldwide (3)
Content: 7.5 mL

Availability

(3)For availability in your country please contact your local representative.
 
130-019-201 $2,750.00

CliniMACS Anti-Biotin Reagent

Availability: Europe (1), USA (2), other (3)
Content: 7.5 mL

Availability

(1)In the EU, the CliniMACS System components are available as CE-marked medical devices for their respective intended use, unless otherwise stated.
(2)In the US, the CliniMACS CD34 Reagent System, including the CliniMACS Plus Instrument, CliniMACS CD34 Reagent, CliniMACS Tubing Sets TS and LS, and the CliniMACS PBS/EDTA Buffer, is FDA approved. All other products of the CliniMACS Product Line are available for use only under an approved Investigational New Drug (IND) application or Investigational Device Exemption (IDE).
(3)For availability in your country please contact your local representative.
 
173-01 price on request here

CliniMACS CD1c (BDCA-1)-Biotin for Research Use

Regulatory status: For research use only, not for use in humans
Availability: worldwide (2)
Content: 5 mL

Availability

(2)For availability in your country please contact your local representative.
 
130-025-501 $2,750.00

CliniMACS CD3 MicroBeads

Regulatory status: For research use only, not for use in humans
Availability: worldwide (3)
Content: 7.5 mL

Availability

(3)For availability in your country please contact your local representative.
 
130-017-601 $3,450.00

CliniMACS CD3 Reagent

Availability: Europe (1), USA (2), other (3)
Content: 7.5 mL

Availability

(1)In the EU, the CliniMACS System components are available as CE-marked medical devices for their respective intended use, unless otherwise stated.
(2)In the US, the CliniMACS CD34 Reagent System, including the CliniMACS Plus Instrument, CliniMACS CD34 Reagent, CliniMACS Tubing Sets TS and LS, and the CliniMACS PBS/EDTA Buffer, is FDA approved. All other products of the CliniMACS Product Line are available for use only under an approved Investigational New Drug (IND) application or Investigational Device Exemption (IDE).
(3)For availability in your country please contact your local representative.
 
273-01 price on request here

CliniMACS CD4 MicroBeads

Regulatory status: For research use only, not for use in humans
Availability: worldwide (3)
Content: 7.5 mL

Availability

(3)For availability in your country please contact your local representative.
 
130-030-401 $3,050.00

CliniMACS CD4 Reagent

Availability: Europe (1), USA (2), other (3)
Content: 7.5 mL

Availability

(1)In the EU, the CliniMACS System components are available as CE-marked medical devices for their respective intended use, unless otherwise stated.
(2)In the US, the CliniMACS CD34 Reagent System, including the CliniMACS Plus Instrument, CliniMACS CD34 Reagent, CliniMACS Tubing Sets TS and LS, and the CliniMACS PBS/EDTA Buffer, is FDA approved. All other products of the CliniMACS Product Line are available for use only under an approved Investigational New Drug (IND) application or Investigational Device Exemption (IDE).
(3)For availability in your country please contact your local representative.
 
276-01 price on request here

CliniMACS CD8 MicroBeads

Regulatory status: For research use only, not for use in humans
Availability: worldwide (3)
Content: 7.5 mL

Availability

(3)For availability in your country please contact your local representative.
 
130-030-801 $3,050.00

CliniMACS CD8 Reagent

Availability: Europe (1), USA (2), other (3)
Content: 7.5 mL

Availability

(1)In the EU, the CliniMACS System components are available as CE-marked medical devices for their respective intended use, unless otherwise stated.
(2)In the US, the CliniMACS CD34 Reagent System, including the CliniMACS Plus Instrument, CliniMACS CD34 Reagent, CliniMACS Tubing Sets TS and LS, and the CliniMACS PBS/EDTA Buffer, is FDA approved. All other products of the CliniMACS Product Line are available for use only under an approved Investigational New Drug (IND) application or Investigational Device Exemption (IDE).
(3)For availability in your country please contact your local representative.
 
275-01 price on request here

CliniMACS CD14 MicroBeads

Regulatory status: For research use only, not for use in humans
Availability: worldwide (3)
Content: 7.5 mL

Availability

(3)For availability in your country please contact your local representative.
 
130-019-101 $2,850.00
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Showing 1-10 of 38


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