Clinical applications - Graft engineering - T cell depletion

T cell depletion

  • Maintenance of effector cells and engraftment facilitating cells
  • Innovative depletion strategies
The aim of active T cell depletion is to maintain a high frequency of graft facilitating and anti-infective functionalities in the graft while displaying a reduced frequency of undesirable T cell functions.

Background

Background

Innovative T cell depletion strategies have been developed to enhance outcome and availability of allogeneic HSCT concepts. Read on to learn about different options and rationales. read more

Reagents

Reagents

Reagents for active T cell depletion, CliniMACS® CD3/CD19 depletion, CliniMACS TCRα/β depletion, and CliniMACS CD45RA depletion read more

Applications

Applications

Active T cell depletion is mainly used in haploidentical stem cell transplantation in combination with reduced intensity conditioning. This concept is not only explored for treatment of malignant disease but also of several non-malignant diseases. read more

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Miltenyi Biotec Inc.
Phone: +1 800 FOR MACS
Fax:+1 877 591 1060
macs@miltenyibiotec.com
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