There are two product lines available for stem cell enrichment. CliniMACS® CD34 enrichment is widely used for enrichment of CD34+ cells from hematopoietic stem cell grafts. The use of these products leads to passive T cell depletion. Stem cell enrichment strategies are widely used for graft-versus-host disease (GvHD) prophylaxis in the context of allogeneic stem cell transplantation. CliniMACS CD133 enrichment has also been used for this purpose, and is also used in tissue regenerative approaches.