Clinical applications - Graft engineering

Graft engineering

  • 15 years experience in cell separation
  • Worldwide use of cell separation (as CD34 enrichtment, CD3/CD19 depletion) in autologous and allogeneic hematopoietic stem cell transplantation

While HSCT is a very effective treatment for certain malignant and non-malignant diseases,41 it is also associated with severe side effects. The CliniMACS® System offers a variety of tools that enables the removal of T cells, T cells subsets, B cells, and other unwanted cells from hematopoietic stem cell grafts. Graft manipulated grafts have been used to overcome relapse and side effects like graft-versus-host disease.1-41

Background

Background

Click here to learn more about the role of our products in graft engineering for HSCT. read more

Stem cell enrichment

Stem cell enrichment

Stem cell enrichment (CD34+ cells) as an effective tool for passive T cell depletion. read more

T cell depletion

T cell depletion

Different strategies for effective T cell depletion (e.g. CD3+ cells) from the graft in allogeneic HSCT. read more

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Miltenyi Biotec Inc.
Phone: +1 800 FOR MACS
Fax:+1 877 591 1060
macs@miltenyibiotec.com
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