Clinical applications - Clinical development - Clinical trial TCRalpha beta-Haplo2010

Clinical trial: TCRalpha/beta-Haplo2010

CliniMACS TCRα/β and CD19 depleted stem cell grafts from haploidentical donors for hematopoietic progenitor cell transplantation in children and adults.

TCRalpha/beta-Haplo2010 is a multi-center Phase I/II trial that will enroll 30 pediatric patients and 30 adult patients in Germany.
The main objective of the trial is the evaluation of the safety/tolerability and feasibility of haploidentical peripheral blood stem cell grafts depleted of TCRα/β+ and CD19+ cells using the CliniMACS TCRα/β and CD19 Systems in patients with hematological and non-hematological malignancies and specific non-malignant diseases, defined as the incidence of grade II–IV acute graft-versus-host disease (GVHD) on Day 100 post-transplantation.

Further information is available from the EU Clinical Trials Register.

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Miltenyi Biotec Inc.
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Fax:+1 877 591 1060
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