Cell separation – faster and more reliable than ever
Magnetic cell separation has become a common method for isolating
specific cell types from blood samples, dissociated tissues, and cell
suspensions. Miltenyi Biotec has just launched the automated MultiMACS
X device, which enables parallel and reliable processing of up to 24
samples or large volumes. This fully automated solution reduces labor
and minimizes contamination risks.
25 years ago, Miltenyi Biotec developed the first MACS® Columns that
enabled scientists to perform magnetic cell separation in their own labs.
Since then, this technology has been continuously optimized and its
applications have become more user-friendly. Miltenyi Biotec’s MultiMACS X
device now allows fully automated performance of all
steps, as well as standardized handling of large volumes, high cell
numbers, or up to 24 samples in parallel. This process enables the user to
continue working with the isolated cell type of interest after just 40
Starting material for cell separation can be various blood products,
mononuclear cells from peripheral blood, as well as dissociated tissues.
All of these samples can be subjected to positive cell isolation as well as
depletion strategies. Like most of Miltenyi Biotec’s equipment, the
MultiMACS X device reduces workload in the lab substantially. “An
intuitively operated touchscreen ensures easy handling while the fully
automated cell separation procedure saves valuable manpower and provides
reliable and reproducible results,” states Dr. Oliver Schilling, Senior
Project Leader, MultiMACS X Development Team at Miltenyi Biotec.
Thanks to its optimized, compact design, the MultiMACS X is easy to
integrate into any lab and can be used either as a stand-alone-device or as
a module in a fully automated cell processing system. “With the MultiMACS
X, we have succeeded in developing a device that offers flexible and
versatile applications and therefore can be used in the pharma or biotech
industry as well as in routine labs “, says Dr. Schilling.
Cell labeling and separation with the MultiMACS X instrument is based on
MACS Technology, which has been cited in more than 20.000 publications.
This technology represents the gentlest way of separating cells available
on the market and can be applied to nearly any cell type. This is made
possible by combining Miltenyi Biotec equipment with the superparamagnetic
MACS MicroBeads and the steep magnetic gradient of the MACS Columns.
For more information regarding application options as well as technical
details please see
Meet us at one of the following events:
November 6–8, 2017 BIO-Europe, Berlin, Germany
November 7–11, 2017 Annual Meeting Society for Neuroscience (Sfn),
Washington DC, USA
December 2– 5, 2017 ASH Annual Meeting, Atlanta, USA
About Miltenyi Biotec
Miltenyi Biotec is a global provider of products and services that advance
biomedical research and cellular therapy. The company’s innovative tools
support research at every level, from basic research to translational
research to clinical application. This integrated portfolio enables
scientists and clinicians to obtain, analyze, and utilize the cell.
Miltenyi Biotec’s technologies cover techniques of sample preparation, cell
isolation, cell sorting, flow cytometry, cell culture, molecular analysis,
and preclinical imaging. Their more than 25 years of expertise spans
research areas including immunology, stem cell biology, neuroscience, and
cancer, and clinical research areas like hematology, graft engineering, and
apheresis. In their commitment to the scientific community, Miltenyi Biotec
also offers comprehensive scientific support, consultation, and expert
training. Today, Miltenyi Biotec has more than 2,000 employees in 25
countries – all dedicated to helping researchers and clinicians around the
world make a greater impact on science and health. For more information
Dr. Christian Stern