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| Overview |
| Anti-O4 antibodies are suitable for immunolabeling of human, mouse or rat O4+ oligodendrocytes for use with immunohistochemistry or flow cytometry. |
| Details |
Background information
During oligodendrocyte development, late A2B5+ oligodendrocyte progenitors start to express O4. As the cells differentiate, A2B5 expression ceases, whereas O4 expression persists. More mature cells start to synthesize galactocerebroside, MBP, PLP, MOG, and O1. In the peripheral nervous system, O4 expression is found on Schwann cells. |
| Clone | Isotype |
| O4 | Mouse IgM |
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| Products |
| Anti-O4-PE, human, mouse, rat |
- for 100 tests (1)
Download datasheet
130-095-887
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| Anti-O4-APC, human, mouse, rat |
- for 100 tests (1)
Download datasheet
130-095-891
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| Anti-O4-Biotin, human, mouse, rat |
- for 100 tests (2)
Download datasheet
130-095-895
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| (1) One test corresponds to fluorescent labeling of up to 106 cells in a total volume of 100 μL. |
| (2) One test corresponds to labeling of up to 106 cells in a total volume of 100 μL. |
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| References |
| 1. Zhang, S.C. (2001) Nat. Rev. Neurosci. 2: 840–843. |
| 2. Sommer, I. and Schachner, M. (1981) Dev. Biol. 83: 311–327. |
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