| Description |
| Mouse CD5 (Ly-1) MicroBeads can be used for the positive selection or depletion of B-1a cells from peripheral lymphoid organs or blood. The CD5 antigen is expressed on B-1a cells but not on conventional B-2 cells. B-1 cells differ from B-2 cells with regard to origin, development, and tissue distribution and show an antigen-restricted B cell receptor repertoire. CD5 is also highly expressed on T cells. |
| Applications |
| For the isolation of highly pure B-1a cells by positive selection using CD5 MicroBeads, T cells have to be depleted in advance by using CD90 (Thy1.2) MicroBeads. |
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