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| Stemgent® Purified Mouse Anti-Human CD29 Antibody |
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| Description |
| Stemgent® Purified Mouse anti-Human CD29 Antibody was screened on normal human mesenchymal stem cells (MSC) by immunocytochemistry (ICC) and flow cytometry (FC) and selected as the best CD29 antibody for characterizing and/or isolating human mesenchymal stem cells. The CD29 molecule is a 130 kDa single chain type I glycoprotein (also known as integrin β1 chain subunit) that is expressed in a heterodimeric complex with one of six distinct α subunits, comprising the very late activation antigen (VLA) subfamily of adhesion receptors. It is one of the essential surface molecules expressed on human MSC from bone marrow and other sources1-3. The β1 subunit is also broadly expressed on lymphocytes and monocytes, weakly expressed on granulocytes, and not expressed on erythrocytes. These receptors are involved in a variety of cell-cell and cell-matrix interactions4-6. |
| Clone | Isotype |
| TS2/16 | Mouse IgG1κ |
| Specifications and technical documents |
| Specification SheetsMaterial Safety Data SheetsProtocols
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| Figure 1 |
| Immunocytochemistry Analysis of Human MSCs. |
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| Figure 2 |
| Flow Cytometry Analysis of Human MSCs. |
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| Favorites / Prices |
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| Details |
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| Products |
| Stemgent Purified Mouse Anti-Human CD29 Antibody |
- 50 μg
- Stemgent Catalog #09-0025
130-095-637
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| References |
| 1. Pittenger, M.F. et al. (1999) Science 284: 143–147. |
| 2. Campagnoli et al. (2001) Blood 98: 2396–2402. |
| 3. Lee et al. (2004) Cell Physiol Biochem 14: 311–324. |
| 4. Cervella et al. (1993) J Biol Chem 268: 5148–5155. |
| 5. Hemler and Lobb (1995) Curr Opin Hematol 2: 61–67. |
| 6. Brakebusch and Fassler (2005) Cancer Metastasis Rev 24: 403–411. |
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