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  • MACS® Cell Analysis
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Cell separation reagents Cell separation reagents
  for human cells
  for non-human primate cells
  for mouse cells
  Stem and progenitor cells
  Neural cells
  T cells
  NK cells
  B cells
  Monocytes and macrophages
  Myeloid derived suppressor cells
  Dendritic cells
  Antigen-presenting cells
  Granulocytes
  Leukocytes
  Endothelial cells
  Erythroid cells
  Cytokine-producing cells
  for rat cells
  for indirect magnetic labeling
  for apoptotic and dead cells
  for isolation of mitochondria
Manual cell separation Manual cell separation
Automated cell separation Automated cell separation
MACS® Technology MACS® Technology
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Anti-NKp46 MicroBead Kit
Description
The Anti-NKp46 MicroBead Kit is an indirect magnetic labeling system for the enrichment of mouse NK cells. NKp46+ cells are labeled with Anti-NKp46-Biotin and Anti-Biotin MicroBeads for subsequent magnetic separation.
Due to the nature of the antibody, a limited degree of pre-activation might occur after cell separation with this product.
Details
Background information
NKp46, also known as MAR-1 or CD335, is a type I transmembrane protein with two extracellular Ig-like domains. It is a member of the natural cytotoxicity receptor (NCR) family, which triggers cytotoxicity in NK cells. NKp46 is involved in target cell recognition and lysis and seems to be exclusively expressed on NK cells. Expression has been shown on BALB/c, SJL, CBA/CA, C57Bl/6, NOD, DBA/2, and B6.129 mice1.
Columns
MS or autoMACS® Columns
 
NKp46+ NK cells were isolated from BALB/c mouse spleen using the Anti-NKp46 MicroBead Kit, two consecutive MS Columns, and a MiniMACS™ Separator. Cells were fluorescently stained with CD3ε-APC and Anti-NKp46-PE and analyzed by flow cytometry using the MACSQuant® Analyzer.
Before separation
After separation
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Details
Products
Anti-NKp46 MicroBead Kit, mouse
- for 109 total cells
Download datasheet
130-095-390
Qty.:
 

Related products
CD49b (DX5) antibodies
Anti-NK1.1 antibodies
Anti-NKp46 antibodies
Anti-KLRG1 antibodies
References
1. Walzer, T. et al. (2007) Proc. Natl. Acad. Sci. USA 104: 3348–3389.
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