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| Overview |
| The CD117 antibody guarantees optimal detection and quantification of CD117+ cells during flow cytometry or fluorescence microscopy experiments. |
| Details |
Background information Clone 3C1 recognizes mouse CD117, a 145 kDa cell surface glycoprotein belonging to the Class III receptor tyrosine kinase family. CD117 is also known as c-kit and stem cell factor (SCF) receptor. It is expressed on the majority of hematopoietic progenitor cells including multipotent hematopoietic stem cells as well as some committed myeloid, erythroid, and lymphoid precursor cells and mature mast cells. CD117+ stem cells from murine bone marrow could also be differentiated into smooth muscle cells, myocytes, and endothelial cells in vivo.1,2 |
| Clone | Isotype |
| 3C1 | Rat IgG2b |
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| Figure 1 |
| Flow cytometric analysis of mouse bone marrow cells using CD117-PE (A) or CD117-APC (B). |
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| B |
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| Favorites / Prices |
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| Details |
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| Products |
| CD117-PE, mouse |
- for 100 tests (1) Download datasheet 130-091-730
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| CD117-APC, mouse |
- for 100 tests (1) Download datasheet 130-091-729
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| (1) One test corresponds to fluorescent labeling of up to 107 cells in a total volume of 100 μL. |
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| References |
| 1. Orlic (2002) Int. J. Hematol. 76 Suppl.1: 144–145. |
| 2. Orlic et al. (2001) Proc. Natl. Acad. Sci. USA 98: 10344–10349. |
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