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CD117
Overview
The CD117 antibody guarantees optimal detection and quantification of CD117+ cells during flow cytometry or fluorescence microscopy experiments.
Details
Background information
Clone 3C1 recognizes mouse CD117, a 145 kDa cell surface glycoprotein belonging to the Class III receptor tyrosine kinase family. CD117 is also known as c-kit and stem cell factor (SCF) receptor. It is expressed on the majority of hematopoietic progenitor cells including multipotent hematopoietic stem cells as well as some committed myeloid, erythroid, and lymphoid precursor cells and mature mast cells. CD117+ stem cells from murine bone marrow could also be differentiated into smooth muscle cells, myocytes, and endothelial cells in vivo.1,2
Clone Isotype
3C1Rat IgG2b
 
Figure 1
Flow cytometric analysis of mouse bone marrow cells using CD117-PE (A) or CD117-APC (B).
A
B
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Products
CD117-PE, mouse
- for 100 tests (1)
Download datasheet
130-091-730
Qty.:
 

CD117-APC, mouse
- for 100 tests (1)
Download datasheet
130-091-729
Qty.:
 

(1) One test corresponds to fluorescent labeling of up to 107 cells in a total volume of 100 μL.
Related products
Lineage Cell Depletion Kit, mouse (#130-090-858)
CD117 MicroBeads, mouse (#130-091-224)
Anti-Sca-1
Lineage Cell Detection Cocktail-Biotin, mouse (#130-092-613)
References
1. Orlic (2002) Int. J. Hematol. 76 Suppl.1: 144–145.
2. Orlic et al. (2001) Proc. Natl. Acad. Sci. USA 98: 10344–10349.
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