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| Overview |
| Clone DG3 recognizes the CD90 antigen, also known as Thy-1, and is suitable for the identification and enumeration of human CD90+ cells by flow cytometry or fluorescence microscopy. |
| Details |
Background information CD90 is a 25–35 kD GPI-anchored protein of the Ig superfamily. It is expressed on, neurons, small subsets of human fetal liver cells and thymocytes, cord blood and bone marrow cells. CD90 is also expressed on a subset of CD34+ primitive hematopoietic stem cells. CD90+CD34+ cells characterize a highly enriched population of high proliferative potential colony-forming cells (HPP-CFC)1. Furthermore, CD90 expression is found on mesenchymal stromal cells (MSCs)2. CD90 is involved in regulation of adhesion and signal transduction of T cells. |
| Clone | Isotype |
| DG3 | Mouse IgG1 |
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HUVECs (human umbilical venous endothelial cells) were stained with CD90 antibodies conjugated to FITC (A), PE (B), or APC (C), and analyzed using the MACSQuant® Analyzer. The lines on the right represent CD90 staining, the lines on the left represent isotype controls. |
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| Details |
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| Products |
| CD90-FITC, human |
- for 100 tests (1) Download datasheet 130-095-403
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| CD90-PE, human |
- for 100 tests (1) Download datasheet 130-095-400
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| CD90-APC, human |
- for 100 tests (1) Download datasheet 130-095-402
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| (1) One test corresponds to fluorescent labeling of up to 107 cells in a total volume of 100 µL |
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| References |
| 1. Mayani and Lansdorp et al. (1994) Blood 83: 2410–2417. |
| 2. Dominici et al. (2006) Cytotherapy 8: 315–317. |
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