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| Stemgent® Sox2 mRNA, human |
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| Description |
Stemgent Sox2 mRNA encodes the Sox2 protein commonly used in cellular reprogramming systems for the generation of induced pluripotent stem (iPS) cells. This in vitro transcribed mRNA incorporates both pseudouridine and 5-methylcytidine modified nucleotides to minimize the cellular interferon response to single stranded RNA.1,2 Repeated transfection of Sox2 mRNA in combination with mRNAs encoding Oct4, Klf4, Lin-28 and c-Myc has been shown to reprogram human fibroblasts.2
Learn more about the Stemgent mRNA Reprogramming System. |
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| This Stemgent® Product is exclusively distributed by Miltenyi Biotec outside the USA and Israel. |
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| Specification SheetsMaterial Safety Data SheetsManuals
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| Details |
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| Products |
| Stemgent Sox2 mRNA, human |
- 20 μg
- Stemgent Catalog #05-0016
130-096-527
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| References |
| 1. Angel, M., Yanik, M.F. (2010) PLoS One 5: e11756. |
| 2. Warren, L. et al. (2010) Cell Stem Cell 7: 618. |
| 3. Yakubov, E., Rechavi, G., Rozenblatt, S., Givol, D. (2010) Biochem. Biophys. Res. Commun. 394: 189. |
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