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| Stemgent® c-Myc mRNA, human |
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| Description |
Stemgent c-Myc mRNA encodes the c-Myc protein commonly used in cellular reprogramming systems for the generation of induced pluripotent stem (iPS) cells. This in vitro transcribed mRNA incorporates both pseudouridine and 5-methylcytidine modified nucleotides to minimize the cellular interferon response to single stranded RNA.1,2 Repeated transfection of c-Myc mRNA in combination with mRNAs encoding Oct4, Klf4, Sox2 and Lin-28 has been shown to reprogram human fibroblasts.2
Learn more about the Stemgent mRNA Reprogramming System. |
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| This Stemgent® Product is exclusively distributed by Miltenyi Biotec outside the USA and Israel. |
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| Details |
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| Products |
| Stemgent c-Myc mRNA, human |
- 20 μg
- Stemgent Catalog #05-0018
130-096-523
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| References |
| 1. Angel, M., Yanik, M.F. (2010) PLoS One 5: e11756. |
| 2. Warren, L. et al. (2010) Cell Stem Cell 7: 618. |
| 3. Yakubov, E., Rechavi, G., Rozenblatt, S., Givol, D. (2010) Biochem. Biophys. Res. Commun. 394: 189. |
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