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| Description |
| Stemolecule™ Ku-006379 is a highly specific small molecule inhibitor of the mammalian target of rapamycin (mTOR)1. The mTOR protein kinase lies at the center of signaling pathways that regulate cell growth and proliferation. Ku-006379 suppresses cell growth and induces a G1 cell cycle arrest by inhibiting two mTOR complexes, mTOR1 and mTOR2, but does not inhibit a large number of other protein kinases1. Since mTOR positively affects protein synthesis and consequently affects both cell survival and cell proliferation, Stemolecule™ Ku-0063794 may be useful in studies in these areas. |
| Disclaimer |
| This Stemgent® Product is exclusively distributed by Miltenyi Biotec outside the USA and Israel. |
| Specifications and technical documents |
| Specification SheetsMaterial Safety Data Sheets
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| Details |
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| Products |
| Stemolecule Ku-0063794 |
- 2 mg - Stemgent Catalog # 04-0050 130-095-593
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| References |
| 1. Garcia-Martinez et al. (2009) Biochem J 421: 29–42. |
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