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| Description |
| Stemolecule™ Forskolin is a natural compound produced by the Indian Coleus plant (Coleus forskohlii)1. It is used in several differentiation protocols for its ability to potentiate neuron differentiation2,3. Forskolin is able to stimulate adenylate cyclase activity and increases cyclic AMP4. Cyclic AMP is a signaling molecule and key regulator of critical enzymes in cellular processes5. For example, cAMP can bind to protein kinase A (PKA) regulatory subunit and activate PKA which acts as a negative regulator of the hedgehog signaling pathway6. |
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| This Stemgent® Product is exclusively distributed by Miltenyi Biotec outside the USA and Israel. |
| Specifications and technical documents |
| Specification SheetsMaterial Safety Data Sheets
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| Details |
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| Products |
| Stemolecule Forskolin |
- 10 mg
- Stemgent Catalog # 04-0025
130-095-575
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| References |
| 1. Chen et al. (1998) Lab Invest 78: 165–174. |
| 2. Son et al. (2001) Neurosci Lett 308: 37–40. |
| 3. Palmer et al. (1997) Mol Cell Neurosci 8: 389–404. |
| 4. Hedin and Rosberg (1983) Mol Cell Endocrinol 33: 69–80. |
| 5. Sands and Palmer (2008) Cell Signal 20: 460–466. |
| 6. Hammerschmidt et al. (1996) Genes Dev 10: 647–658. |
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